The Immunogenicity and Safety of <i>Mycobacterium tuberculosis</i>-<i>mosR</i>-Based Double Deletion Strain in Mice

The Immunogenicity and Safety of <i>Mycobacterium tuberculosis</i>-<i>mosR</i>-Based Double Deletion Strain in Mice

<i>Mycobacterium tuberculosis</i> (<i>M. tuberculosis</i>) remains a significant global health threat, accounting for ~1.7 million deaths annually. The efficacy of the current vaccine, <i>M. bovis</i> BCG, ranges from 0 to 80% in children and does not prevent adul...

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Bibliographic Details
Main Authors: Rachel E. Hildebrand, Chungyi Hansen, Brock Kingstad-Bakke, Chia-Wei Wu, Marulasiddappa Suresh, Adel Talaat
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Microorganisms
Subjects:
tuberculosis vaccine
mycobacteria
safety
immunology
Online Access:https://www.mdpi.com/2076-2607/11/8/2105

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