RNA-sequencing data analysis of uterus in ovariectomized rats fed with soy protein isolate, 17β-estradiol and casein
This data file describes the bioinformatics analysis of uterine RNA-seq data comparing genome wide effects of feeding soy protein isolate compared to casein to ovariectomized female rats age 64 days relative to treatment of casein fed rats with 5 μg/kg/d estradiol and relative to rats treated with e...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2016-06-01
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| Series: | Data in Brief |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2352340916302475 |
| _version_ | 1819001125135712256 |
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| author | Martin J. Ronis Horacio Gomez-Acevedo Michael L. Blackburn Mario A. Cleves Rohit Singhal Thomas M. Badger |
| author_facet | Martin J. Ronis Horacio Gomez-Acevedo Michael L. Blackburn Mario A. Cleves Rohit Singhal Thomas M. Badger |
| author_sort | Martin J. Ronis |
| collection | DOAJ |
| description | This data file describes the bioinformatics analysis of uterine RNA-seq data comparing genome wide effects of feeding soy protein isolate compared to casein to ovariectomized female rats age 64 days relative to treatment of casein fed rats with 5 μg/kg/d estradiol and relative to rats treated with estradiol and also fed soy protein isolate. Complete raw data files were deposited in the gene Expression Omnibus (GEO) at NCBI (http:/www.ncbi.nlm.nih.gov.geo/) under the GEO accession number GEO: GSE69819. Data presented here incudes a summary of the differential expression analysis with top 30 genes up- and down-regulated by soy protein isolate (SPI), estradiol (E2) and SPI+E2. Additional functional annotation analysis of KEGG pathways is also presented for each treatment, together with networks of interaction between those pathways. Further interpretation and discussion of this data can be found in the article “Uterine responses to feeding soy protein isolate and treatment with 17β-estradiol differ in ovariectomized female rats” Ronis et al. (2016) [1]. |
| first_indexed | 2024-12-20T22:44:14Z |
| format | Article |
| id | doaj.art-4168a254fd9742b0b9b5476596a0194f |
| institution | Directory Open Access Journal |
| issn | 2352-3409 |
| language | English |
| last_indexed | 2024-12-20T22:44:14Z |
| publishDate | 2016-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Data in Brief |
| spelling | doaj.art-4168a254fd9742b0b9b5476596a0194f2022-12-21T19:24:24ZengElsevierData in Brief2352-34092016-06-01714911496RNA-sequencing data analysis of uterus in ovariectomized rats fed with soy protein isolate, 17β-estradiol and caseinMartin J. Ronis0Horacio Gomez-Acevedo1Michael L. Blackburn2Mario A. Cleves3Rohit Singhal4Thomas M. Badger5Department of Pharmacology & Experimental Therapeutics, LSUHSC-New Orelans, New Orleans, LA, United States; Arkansas Children’s Nutrition Center, Little Rock, AR, United States; Corresponding author at: Department of Pharmacology & Experimental Therapeutics, LSUHSC-New Orelans, New Orleans, LA, United States.Arkansas Children’s Nutrition Center, Little Rock, AR, United States; Department of Biomedical Informatics, UAMS, Little Rock, AR, United StatesArkansas Children’s Nutrition Center, Little Rock, AR, United StatesArkansas Children’s Nutrition Center, Little Rock, AR, United StatesArkansas Children’s Nutrition Center, Little Rock, AR, United StatesArkansas Children’s Nutrition Center, Little Rock, AR, United StatesThis data file describes the bioinformatics analysis of uterine RNA-seq data comparing genome wide effects of feeding soy protein isolate compared to casein to ovariectomized female rats age 64 days relative to treatment of casein fed rats with 5 μg/kg/d estradiol and relative to rats treated with estradiol and also fed soy protein isolate. Complete raw data files were deposited in the gene Expression Omnibus (GEO) at NCBI (http:/www.ncbi.nlm.nih.gov.geo/) under the GEO accession number GEO: GSE69819. Data presented here incudes a summary of the differential expression analysis with top 30 genes up- and down-regulated by soy protein isolate (SPI), estradiol (E2) and SPI+E2. Additional functional annotation analysis of KEGG pathways is also presented for each treatment, together with networks of interaction between those pathways. Further interpretation and discussion of this data can be found in the article “Uterine responses to feeding soy protein isolate and treatment with 17β-estradiol differ in ovariectomized female rats” Ronis et al. (2016) [1].http://www.sciencedirect.com/science/article/pii/S2352340916302475 |
| spellingShingle | Martin J. Ronis Horacio Gomez-Acevedo Michael L. Blackburn Mario A. Cleves Rohit Singhal Thomas M. Badger RNA-sequencing data analysis of uterus in ovariectomized rats fed with soy protein isolate, 17β-estradiol and casein Data in Brief |
| title | RNA-sequencing data analysis of uterus in ovariectomized rats fed with soy protein isolate, 17β-estradiol and casein |
| title_full | RNA-sequencing data analysis of uterus in ovariectomized rats fed with soy protein isolate, 17β-estradiol and casein |
| title_fullStr | RNA-sequencing data analysis of uterus in ovariectomized rats fed with soy protein isolate, 17β-estradiol and casein |
| title_full_unstemmed | RNA-sequencing data analysis of uterus in ovariectomized rats fed with soy protein isolate, 17β-estradiol and casein |
| title_short | RNA-sequencing data analysis of uterus in ovariectomized rats fed with soy protein isolate, 17β-estradiol and casein |
| title_sort | rna sequencing data analysis of uterus in ovariectomized rats fed with soy protein isolate 17β estradiol and casein |
| url | http://www.sciencedirect.com/science/article/pii/S2352340916302475 |
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