Noninvasive Diabetes Detection through Human Breath Using TinyML-Powered E-Nose

Volatile organic compounds (VOCs) in exhaled human breath serve as pivotal biomarkers for disease identification and medical diagnostics. In the context of diabetes mellitus, the noninvasive detection of acetone, a primary biomarker using electronic noses (e-noses), has gained significant attention....

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Main Authors: Alberto Gudiño-Ochoa, Julio Alberto García-Rodríguez, Raquel Ochoa-Ornelas, Jorge Ivan Cuevas-Chávez, Daniel Alejandro Sánchez-Arias
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:Sensors
Subjects:
Online Access:https://www.mdpi.com/1424-8220/24/4/1294
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author Alberto Gudiño-Ochoa
Julio Alberto García-Rodríguez
Raquel Ochoa-Ornelas
Jorge Ivan Cuevas-Chávez
Daniel Alejandro Sánchez-Arias
author_facet Alberto Gudiño-Ochoa
Julio Alberto García-Rodríguez
Raquel Ochoa-Ornelas
Jorge Ivan Cuevas-Chávez
Daniel Alejandro Sánchez-Arias
author_sort Alberto Gudiño-Ochoa
collection DOAJ
description Volatile organic compounds (VOCs) in exhaled human breath serve as pivotal biomarkers for disease identification and medical diagnostics. In the context of diabetes mellitus, the noninvasive detection of acetone, a primary biomarker using electronic noses (e-noses), has gained significant attention. However, employing e-noses requires pre-trained algorithms for precise diabetes detection, often requiring a computer with a programming environment to classify newly acquired data. This study focuses on the development of an embedded system integrating Tiny Machine Learning (TinyML) and an e-nose equipped with Metal Oxide Semiconductor (MOS) sensors for real-time diabetes detection. The study encompassed 44 individuals, comprising 22 healthy individuals and 22 diagnosed with various types of diabetes mellitus. Test results highlight the XGBoost Machine Learning algorithm’s achievement of 95% detection accuracy. Additionally, the integration of deep learning algorithms, particularly deep neural networks (DNNs) and one-dimensional convolutional neural network (1D-CNN), yielded a detection efficacy of 94.44%. These outcomes underscore the potency of combining e-noses with TinyML in embedded systems, offering a noninvasive approach for diabetes mellitus detection.
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spelling doaj.art-4169115f9ad44994af3b8958305886542024-02-23T15:34:05ZengMDPI AGSensors1424-82202024-02-01244129410.3390/s24041294Noninvasive Diabetes Detection through Human Breath Using TinyML-Powered E-NoseAlberto Gudiño-Ochoa0Julio Alberto García-Rodríguez1Raquel Ochoa-Ornelas2Jorge Ivan Cuevas-Chávez3Daniel Alejandro Sánchez-Arias4Electronics Department, Tecnológico Nacional de México/Instituto Tecnológico de Ciudad Guzmán, Ciudad Guzmán 49100, MexicoCentro Universitario del Sur, Departamento de Ciencias Computacionales e Innovación Tecnológica, Universidad de Guadalajara, Ciudad Guzmán 49000, MexicoSystems and Computation Department, Tecnológico Nacional de México/Instituto Tecnológico de Ciudad Guzmán, Ciudad Guzmán 49100, MexicoElectronics Department, Tecnológico Nacional de México/Instituto Tecnológico de Ciudad Guzmán, Ciudad Guzmán 49100, MexicoElectronics Department, Tecnológico Nacional de México/Instituto Tecnológico de Ciudad Guzmán, Ciudad Guzmán 49100, MexicoVolatile organic compounds (VOCs) in exhaled human breath serve as pivotal biomarkers for disease identification and medical diagnostics. In the context of diabetes mellitus, the noninvasive detection of acetone, a primary biomarker using electronic noses (e-noses), has gained significant attention. However, employing e-noses requires pre-trained algorithms for precise diabetes detection, often requiring a computer with a programming environment to classify newly acquired data. This study focuses on the development of an embedded system integrating Tiny Machine Learning (TinyML) and an e-nose equipped with Metal Oxide Semiconductor (MOS) sensors for real-time diabetes detection. The study encompassed 44 individuals, comprising 22 healthy individuals and 22 diagnosed with various types of diabetes mellitus. Test results highlight the XGBoost Machine Learning algorithm’s achievement of 95% detection accuracy. Additionally, the integration of deep learning algorithms, particularly deep neural networks (DNNs) and one-dimensional convolutional neural network (1D-CNN), yielded a detection efficacy of 94.44%. These outcomes underscore the potency of combining e-noses with TinyML in embedded systems, offering a noninvasive approach for diabetes mellitus detection.https://www.mdpi.com/1424-8220/24/4/1294electronic nosediabetes mellitusTinyMLexhaled-breath analysisVOCsTensorFlowLite
spellingShingle Alberto Gudiño-Ochoa
Julio Alberto García-Rodríguez
Raquel Ochoa-Ornelas
Jorge Ivan Cuevas-Chávez
Daniel Alejandro Sánchez-Arias
Noninvasive Diabetes Detection through Human Breath Using TinyML-Powered E-Nose
Sensors
electronic nose
diabetes mellitus
TinyML
exhaled-breath analysis
VOCs
TensorFlowLite
title Noninvasive Diabetes Detection through Human Breath Using TinyML-Powered E-Nose
title_full Noninvasive Diabetes Detection through Human Breath Using TinyML-Powered E-Nose
title_fullStr Noninvasive Diabetes Detection through Human Breath Using TinyML-Powered E-Nose
title_full_unstemmed Noninvasive Diabetes Detection through Human Breath Using TinyML-Powered E-Nose
title_short Noninvasive Diabetes Detection through Human Breath Using TinyML-Powered E-Nose
title_sort noninvasive diabetes detection through human breath using tinyml powered e nose
topic electronic nose
diabetes mellitus
TinyML
exhaled-breath analysis
VOCs
TensorFlowLite
url https://www.mdpi.com/1424-8220/24/4/1294
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