Cytokine expression in gingival crevicular fluid around teeth opposing dental implants and 3-unit fixed partial dentures in a cross-sectional study
Abstract Objective This study aimed to study the cytokines in gingival crevicular fluid (GCF) of the teeth opposing to dental implants and 3-unit fixed partial dentures (FPDs). Materials and methods A total of 74 participants were recruited for this cross-sectional study. Based on the status of lowe...
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| Language: | English |
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BMC
2023-04-01
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| Series: | Head & Face Medicine |
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| Online Access: | https://doi.org/10.1186/s13005-023-00359-0 |
| _version_ | 1797845734875201536 |
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| author | Xin-Rui Zhu Chen-Xi Wang Chang Chen Rui-Yong Wang Yu Zhang |
| author_facet | Xin-Rui Zhu Chen-Xi Wang Chang Chen Rui-Yong Wang Yu Zhang |
| author_sort | Xin-Rui Zhu |
| collection | DOAJ |
| description | Abstract Objective This study aimed to study the cytokines in gingival crevicular fluid (GCF) of the teeth opposing to dental implants and 3-unit fixed partial dentures (FPDs). Materials and methods A total of 74 participants were recruited for this cross-sectional study. Based on the status of lower first molars, the participants were divided into dental implants group and 3-unit FPDs group. Social index and oral hygiene were recorded. Occlusal loading was evaluated with a T-scan. GCF was sampled from the upper first molar and assessed with a commercial cytokine assay kit. Results Forty three dental implants patients and 31 3-unit FPDs patients received all of the clinical and laboratory evaluation. The dental implants group had a higher occlusion force distribution on first molars region. IL-10, IL-17, RANK had a higher mean in dental implants group and was associated with occlusion force of first molar. There was a weakly association between IL-10 and dental implants in the binary logistic regression analyses. Conclusions In this study, the teeth opposing implants have a higher level of cytokines in the GCF than teeth opposing to 3-unit FPDs in periodontal healthy participants because of the poor osseoperception of dental implants. IL-10 might reflect a higher occlusion force in dental implants region. Clinical relevance This study provided that different tooth restoration methods could influence the periodontal status of the contact teeth. |
| first_indexed | 2024-04-09T17:43:43Z |
| format | Article |
| id | doaj.art-416e287852d84daabe509a1ac7bd5bc5 |
| institution | Directory Open Access Journal |
| issn | 1746-160X |
| language | English |
| last_indexed | 2024-04-09T17:43:43Z |
| publishDate | 2023-04-01 |
| publisher | BMC |
| record_format | Article |
| series | Head & Face Medicine |
| spelling | doaj.art-416e287852d84daabe509a1ac7bd5bc52023-04-16T11:26:20ZengBMCHead & Face Medicine1746-160X2023-04-011911910.1186/s13005-023-00359-0Cytokine expression in gingival crevicular fluid around teeth opposing dental implants and 3-unit fixed partial dentures in a cross-sectional studyXin-Rui Zhu0Chen-Xi Wang1Chang Chen2Rui-Yong Wang3Yu Zhang4Department of Stomatology, Beijing Haidian HospitalDepartment of Oral Implantology, Peking University School and Hospital of StomatologyDepartment of General Dentistry, Shanghai Ninth People’s Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine & National Clinical Research Center for Oral Diseases & Shanghai Key Laboratory of Stomatology & Shanghai Research Institute of StomatologyDepartment of Stomatology, Beijing Haidian HospitalDepartment of Oral Implantology, Peking University School and Hospital of StomatologyAbstract Objective This study aimed to study the cytokines in gingival crevicular fluid (GCF) of the teeth opposing to dental implants and 3-unit fixed partial dentures (FPDs). Materials and methods A total of 74 participants were recruited for this cross-sectional study. Based on the status of lower first molars, the participants were divided into dental implants group and 3-unit FPDs group. Social index and oral hygiene were recorded. Occlusal loading was evaluated with a T-scan. GCF was sampled from the upper first molar and assessed with a commercial cytokine assay kit. Results Forty three dental implants patients and 31 3-unit FPDs patients received all of the clinical and laboratory evaluation. The dental implants group had a higher occlusion force distribution on first molars region. IL-10, IL-17, RANK had a higher mean in dental implants group and was associated with occlusion force of first molar. There was a weakly association between IL-10 and dental implants in the binary logistic regression analyses. Conclusions In this study, the teeth opposing implants have a higher level of cytokines in the GCF than teeth opposing to 3-unit FPDs in periodontal healthy participants because of the poor osseoperception of dental implants. IL-10 might reflect a higher occlusion force in dental implants region. Clinical relevance This study provided that different tooth restoration methods could influence the periodontal status of the contact teeth.https://doi.org/10.1186/s13005-023-00359-0Gingival crevicular fluidCytokinesDental implantsFixed partial denturesContact teeth |
| spellingShingle | Xin-Rui Zhu Chen-Xi Wang Chang Chen Rui-Yong Wang Yu Zhang Cytokine expression in gingival crevicular fluid around teeth opposing dental implants and 3-unit fixed partial dentures in a cross-sectional study Head & Face Medicine Gingival crevicular fluid Cytokines Dental implants Fixed partial dentures Contact teeth |
| title | Cytokine expression in gingival crevicular fluid around teeth opposing dental implants and 3-unit fixed partial dentures in a cross-sectional study |
| title_full | Cytokine expression in gingival crevicular fluid around teeth opposing dental implants and 3-unit fixed partial dentures in a cross-sectional study |
| title_fullStr | Cytokine expression in gingival crevicular fluid around teeth opposing dental implants and 3-unit fixed partial dentures in a cross-sectional study |
| title_full_unstemmed | Cytokine expression in gingival crevicular fluid around teeth opposing dental implants and 3-unit fixed partial dentures in a cross-sectional study |
| title_short | Cytokine expression in gingival crevicular fluid around teeth opposing dental implants and 3-unit fixed partial dentures in a cross-sectional study |
| title_sort | cytokine expression in gingival crevicular fluid around teeth opposing dental implants and 3 unit fixed partial dentures in a cross sectional study |
| topic | Gingival crevicular fluid Cytokines Dental implants Fixed partial dentures Contact teeth |
| url | https://doi.org/10.1186/s13005-023-00359-0 |
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