<i>Carcino-Evo-Devo</i>, A Theory of the Evolutionary Role of Hereditary Tumors
A theory of the evolutionary role of hereditary tumors, or the <i>carcino-evo-devo</i> theory, is being developed. The main hypothesis of the theory, the hypothesis of evolution by tumor neofunctionalization, posits that hereditary tumors provided additional cell masses during the evolut...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-05-01
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| Series: | International Journal of Molecular Sciences |
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| Online Access: | https://www.mdpi.com/1422-0067/24/10/8611 |
| Summary: | A theory of the evolutionary role of hereditary tumors, or the <i>carcino-evo-devo</i> theory, is being developed. The main hypothesis of the theory, the hypothesis of evolution by tumor neofunctionalization, posits that hereditary tumors provided additional cell masses during the evolution of multicellular organisms for the expression of evolutionarily novel genes. The <i>carcino-evo-devo</i> theory has formulated several nontrivial predictions that have been confirmed in the laboratory of the author. It also suggests several nontrivial explanations of biological phenomena previously unexplained by the existing theories or incompletely understood. By considering three major types of biological development—individual, evolutionary, and neoplastic development—within one theoretical framework, the <i>carcino-evo-devo</i> theory has the potential to become a unifying biological theory. |
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| ISSN: | 1661-6596 1422-0067 |