Current Understanding of Bacillus Calmette-Guérin-Mediated Trained Immunity and Its Perspectives for Controlling Intracellular Infections

Current Understanding of Bacillus Calmette-Guérin-Mediated Trained Immunity and Its Perspectives for Controlling Intracellular Infections

The bacillus Calmette–Guérin (BCG) is an attenuated bacterium derived from virulent <i>Mycobacterium bovis</i>. It is the only licensed vaccine used for preventing severe forms of tuberculosis in children. Besides its specific effects against tuberculosis, BCG administration is also asso...

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Bibliographic Details
Main Authors: Ana Carolina V. S. C. de Araujo, Fábio Mambelli, Rodrigo O. Sanches, Fábio V. Marinho, Sergio C. Oliveira
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:Pathogens
Subjects:
BCG
trained immunity
intracellular infections
innate memory
Online Access:https://www.mdpi.com/2076-0817/12/12/1386

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