Minimal Clinically Important Difference of Scales Reported in Stroke Trials: A Review
There is a growing awareness of the significance of using minimum clinically important differences (MCIDs) in stroke research. An MCID is the smallest change in an outcome measure that is considered clinically meaningful. This review is the first to provide a comprehensive summary of various scales...
| প্রধান লেখক: | , , , , , |
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| বিন্যাস: | প্রবন্ধ |
| ভাষা: | English |
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MDPI AG
2024-01-01
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| মালা: | Brain Sciences |
| বিষয়গুলি: | |
| অনলাইন ব্যবহার করুন: | https://www.mdpi.com/2076-3425/14/1/80 |
| _version_ | 1827372595460177920 |
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| author | Biswamohan Mishra Pachipala Sudheer Ayush Agarwal Nilima Nilima Madakasira Vasantha Padma Srivastava Venugopalan Y. Vishnu |
| author_facet | Biswamohan Mishra Pachipala Sudheer Ayush Agarwal Nilima Nilima Madakasira Vasantha Padma Srivastava Venugopalan Y. Vishnu |
| author_sort | Biswamohan Mishra |
| collection | DOAJ |
| description | There is a growing awareness of the significance of using minimum clinically important differences (MCIDs) in stroke research. An MCID is the smallest change in an outcome measure that is considered clinically meaningful. This review is the first to provide a comprehensive summary of various scales and patient-reported outcome measures (PROMs) used in stroke research and their MCID values reported in the literature, including a concise overview of the concept of and methods for determining MCIDs in stroke research. Despite the controversies and limitations surrounding the estimation of MCIDs, their importance in modern clinical trials cannot be overstated. Anchor-based and distribution-based methods are recommended for estimating MCIDs, with patient self-evaluation being a crucial component in capturing the patient’s perspective on their health. A combination of methods can provide a more comprehensive understanding of the clinical relevance of treatment effects, and incorporating the patient’s perspective can enhance the care of stroke patients. |
| first_indexed | 2024-03-08T11:03:08Z |
| format | Article |
| id | doaj.art-417661def2f442c0b71b784d9b7bd241 |
| institution | Directory Open Access Journal |
| issn | 2076-3425 |
| language | English |
| last_indexed | 2024-03-08T11:03:08Z |
| publishDate | 2024-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Brain Sciences |
| spelling | doaj.art-417661def2f442c0b71b784d9b7bd2412024-01-26T15:25:03ZengMDPI AGBrain Sciences2076-34252024-01-011418010.3390/brainsci14010080Minimal Clinically Important Difference of Scales Reported in Stroke Trials: A ReviewBiswamohan Mishra0Pachipala Sudheer1Ayush Agarwal2Nilima Nilima3Madakasira Vasantha Padma Srivastava4Venugopalan Y. Vishnu5Department of Neurology, All India Institute of Medical Sciences, New Delhi 110029, IndiaDepartment of Neurology, All India Institute of Medical Sciences, New Delhi 110029, IndiaDepartment of Neurology, All India Institute of Medical Sciences, New Delhi 110029, IndiaDepartment of Biostatics, All India Institute of Medical Sciences, New Delhi 110029, IndiaDepartment of Neurology, All India Institute of Medical Sciences, New Delhi 110029, IndiaDepartment of Neurology, All India Institute of Medical Sciences, New Delhi 110029, IndiaThere is a growing awareness of the significance of using minimum clinically important differences (MCIDs) in stroke research. An MCID is the smallest change in an outcome measure that is considered clinically meaningful. This review is the first to provide a comprehensive summary of various scales and patient-reported outcome measures (PROMs) used in stroke research and their MCID values reported in the literature, including a concise overview of the concept of and methods for determining MCIDs in stroke research. Despite the controversies and limitations surrounding the estimation of MCIDs, their importance in modern clinical trials cannot be overstated. Anchor-based and distribution-based methods are recommended for estimating MCIDs, with patient self-evaluation being a crucial component in capturing the patient’s perspective on their health. A combination of methods can provide a more comprehensive understanding of the clinical relevance of treatment effects, and incorporating the patient’s perspective can enhance the care of stroke patients.https://www.mdpi.com/2076-3425/14/1/80strokeminimal clinically important differenceminimal clinically important changeclinical relevancepatient-reported outcome measures (PROMs)MCID |
| spellingShingle | Biswamohan Mishra Pachipala Sudheer Ayush Agarwal Nilima Nilima Madakasira Vasantha Padma Srivastava Venugopalan Y. Vishnu Minimal Clinically Important Difference of Scales Reported in Stroke Trials: A Review Brain Sciences stroke minimal clinically important difference minimal clinically important change clinical relevance patient-reported outcome measures (PROMs) MCID |
| title | Minimal Clinically Important Difference of Scales Reported in Stroke Trials: A Review |
| title_full | Minimal Clinically Important Difference of Scales Reported in Stroke Trials: A Review |
| title_fullStr | Minimal Clinically Important Difference of Scales Reported in Stroke Trials: A Review |
| title_full_unstemmed | Minimal Clinically Important Difference of Scales Reported in Stroke Trials: A Review |
| title_short | Minimal Clinically Important Difference of Scales Reported in Stroke Trials: A Review |
| title_sort | minimal clinically important difference of scales reported in stroke trials a review |
| topic | stroke minimal clinically important difference minimal clinically important change clinical relevance patient-reported outcome measures (PROMs) MCID |
| url | https://www.mdpi.com/2076-3425/14/1/80 |
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