Design, Synthesis, and Antiviral Activities of New Benzotriazole-Based Derivatives

Design, Synthesis, and Antiviral Activities of New Benzotriazole-Based Derivatives

Several human diseases are caused by enteroviruses and are currently clinically untreatable, pushing the research to identify new antivirals. A notable number of benzo[<i>d</i>][1,2,3]triazol-1(2)-yl derivatives were designed, synthesized, and in vitro evaluated for cytotoxicity and anti...

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Bibliographic Details
Main Authors: Roberta Ibba, Paola Corona, Francesca Nonne, Paola Caria, Gabriele Serreli, Vanessa Palmas, Federico Riu, Simona Sestito, Maria Nieddu, Roberta Loddo, Giuseppina Sanna, Sandra Piras, Antonio Carta
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Pharmaceuticals
Subjects:
benzotriazoles
antiviral compounds
enterovirus
coxsackievirus B5
RNA-virus
<i>Picornaviridae</i>
Online Access:https://www.mdpi.com/1424-8247/16/3/429

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