Fingolimod Augments Monomethylfumarate Killing of GBM Cells

Fingolimod Augments Monomethylfumarate Killing of GBM Cells

Previously we demonstrated that the multiple sclerosis drug dimethyl fumarate (DMF) and its plasma breakdown product MMF could interact with chemotherapeutic agents to kill both GBM cells and activated microglia. The trial NCT02337426 demonstrated the safety of DMF in newly diagnosed GBM patients wh...

Full description

Bibliographic Details
Main Authors: Paul Dent, Laurence Booth, Jane L. Roberts, Andrew Poklepovic, John F. Hancock
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Oncology
Subjects:
fingolimod
dimethyl fumarate
Gilenya
Tecfidera
RAS
glioblastoma
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.00022/full

Similar Items

Similar Items