Alcohol Exposure Induces Nucleolar Stress and Apoptosis in Mouse Neural Stem Cells and Late-Term Fetal Brain

Alcohol Exposure Induces Nucleolar Stress and Apoptosis in Mouse Neural Stem Cells and Late-Term Fetal Brain

Prenatal alcohol exposure (PAE) is a leading cause of neurodevelopmental disability through its induction of neuronal growth dysfunction through incompletely understood mechanisms. Ribosome biogenesis regulates cell cycle progression through p53 and the nucleolar cell stress response. Whether those...

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Bibliographic Details
Main Authors: Yanping Huang, George R. Flentke, Olivia C. Rivera, Nipun Saini, Sandra M. Mooney, Susan M. Smith
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:Cells
Subjects:
apoptosis
fetal alcohol spectrum disorder
neural stem cells
nucleolar stress
MDM2
p53
Online Access:https://www.mdpi.com/2073-4409/13/5/440

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