Frequency of occurrence of genetic polymorphisms associated with sports success in elite athletes in team sports
Objective: to evaluate the frequency of occurrence of polymorphisms rs1815739 (ACTN3 gene), rs2016520 (PPARD gene), rs1042713 (ADRB2 gene), rs1799945 (HFE gene) in athletes of highperformance sports.Materials and methods: genotyping was performed using allelespecific amplification with realtime d...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
National Electronic Information Consortium (NEICON)
2021-06-01
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| Series: | Спортивная медицина: наука и практика |
| Subjects: | |
| Online Access: | https://www.smjournal.ru/jour/article/view/262 |
| Summary: | Objective: to evaluate the frequency of occurrence of polymorphisms rs1815739 (ACTN3 gene), rs2016520 (PPARD gene), rs1042713 (ADRB2 gene), rs1799945 (HFE gene) in athletes of highperformance sports.Materials and methods: genotyping was performed using allelespecific amplification with realtime detection of the results and using TaqMan probes.Results: a higher frequency of alleles associated with endurance was found: the t allele of the rs1815739 polymorphism (ACTN3 gene), the g allele of the rs2016520 polymorphism (PPARD gene), the g allele of the rs1042713 polymorphism (ADRB2 gene), and the g allele of the rs1799945 polymorphism (HFE gene) in athletes of game sports.Conclusion: the results of genotyping of polymorphisms associated with endurance in the examined athletes showed a higher frequency of occurrence than in the population as a whole. |
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| ISSN: | 2223-2524 2587-9014 |