Accumulation of fibrosis and altered perifollicular stromal differentiation in vitrified‐thawed human ovarian tissue xenografted to nude mice.

Accumulation of fibrosis and altered perifollicular stromal differentiation in vitrified‐thawed human ovarian tissue xenografted to nude mice.

Abstract Purpose Ovarian tissue cryopreservation and its auto‐transplantation is promising technique in fertility preservation. Longevity of grafted tissue is limited though mechanism of follicle reduction is not fully understood. We evaluated histological alteration of vitrified‐thawed ovarian tiss...

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Bibliographic Details
Main Authors: Michio Kitajima, Naoko Murakami, Yuriko Kitajima, Itsuki Kajimura, Asako Matsumura, Kanako Matsumoto, Ayumi Harada, Kiyonori Miura
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:Reproductive Medicine and Biology
Subjects:
alpha‐smooth muscle actin
fibrosis
follicular growth
ovarian cortical stroma
ovarian tissue cryopreservation
Online Access:https://doi.org/10.1002/rmb2.12451

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