Cloning and spatiotemporal expression of Xenopus laevis Apolipoprotein CI.
Apolipoprotein CI (ApoCI) belongs to the Apolipoprotein superfamily, members of which are involved in lipid transport, uptake and homeostasis. Excessive ApoCI has been implicated in atherosclerosis and Alzheimer's disease in humans. In this study we report the isolation of Xenopus laevis apoCI...
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2018-01-01
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| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC5773212?pdf=render |
| _version_ | 1811212039745437696 |
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| author | Jyotsna Sridharan Tomomi Haremaki Daniel C Weinstein |
| author_facet | Jyotsna Sridharan Tomomi Haremaki Daniel C Weinstein |
| author_sort | Jyotsna Sridharan |
| collection | DOAJ |
| description | Apolipoprotein CI (ApoCI) belongs to the Apolipoprotein superfamily, members of which are involved in lipid transport, uptake and homeostasis. Excessive ApoCI has been implicated in atherosclerosis and Alzheimer's disease in humans. In this study we report the isolation of Xenopus laevis apoCI and describe the expression pattern of this gene during early development, using reverse transcription polymerase chain reaction and whole mount in situ hybridization. Xenopus apoCI is enriched in the dorsal ectoderm during gastrulation, and is subsequently expressed in sensory placodes, neural tube and cranial neural crest. These data suggest as yet uncharacterized roles for ApoCI during early vertebrate embryogenesis. |
| first_indexed | 2024-04-12T05:23:15Z |
| format | Article |
| id | doaj.art-41827637082a4394bcd1e0c187704935 |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-04-12T05:23:15Z |
| publishDate | 2018-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-41827637082a4394bcd1e0c1877049352022-12-22T03:46:23ZengPublic Library of Science (PLoS)PLoS ONE1932-62032018-01-01131e019147010.1371/journal.pone.0191470Cloning and spatiotemporal expression of Xenopus laevis Apolipoprotein CI.Jyotsna SridharanTomomi HaremakiDaniel C WeinsteinApolipoprotein CI (ApoCI) belongs to the Apolipoprotein superfamily, members of which are involved in lipid transport, uptake and homeostasis. Excessive ApoCI has been implicated in atherosclerosis and Alzheimer's disease in humans. In this study we report the isolation of Xenopus laevis apoCI and describe the expression pattern of this gene during early development, using reverse transcription polymerase chain reaction and whole mount in situ hybridization. Xenopus apoCI is enriched in the dorsal ectoderm during gastrulation, and is subsequently expressed in sensory placodes, neural tube and cranial neural crest. These data suggest as yet uncharacterized roles for ApoCI during early vertebrate embryogenesis.http://europepmc.org/articles/PMC5773212?pdf=render |
| spellingShingle | Jyotsna Sridharan Tomomi Haremaki Daniel C Weinstein Cloning and spatiotemporal expression of Xenopus laevis Apolipoprotein CI. PLoS ONE |
| title | Cloning and spatiotemporal expression of Xenopus laevis Apolipoprotein CI. |
| title_full | Cloning and spatiotemporal expression of Xenopus laevis Apolipoprotein CI. |
| title_fullStr | Cloning and spatiotemporal expression of Xenopus laevis Apolipoprotein CI. |
| title_full_unstemmed | Cloning and spatiotemporal expression of Xenopus laevis Apolipoprotein CI. |
| title_short | Cloning and spatiotemporal expression of Xenopus laevis Apolipoprotein CI. |
| title_sort | cloning and spatiotemporal expression of xenopus laevis apolipoprotein ci |
| url | http://europepmc.org/articles/PMC5773212?pdf=render |
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