Prime Editing, a Novel Genome-Editing Tool That May Surpass Conventional CRISPR-Cas9

Prime Editing, a Novel Genome-Editing Tool That May Surpass Conventional CRISPR-Cas9

Background: Genome editing mediated by clustered regularly interspaced short palindromic repeat -CRISPR-Cas- was first reported using cell lines in 2012, and since then, its applications in other systems have steadily increased. However, this approach still needs improvement and optimization. Prime...

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Bibliographic Details
Main Authors: Adriana Ochoa-Sanchez, Gabriela Perez-Sanchez, A. Marianna Torres-Ledesma, Juan Pablo R. Valdez, Gabriel Rinaldi, B?rbara B. Moguel, Christian Molina-Aguilar
Format: Article
Language:English
Published: Mary Ann Liebert 2021-01-01
Series:Re:GEN Open
Subjects:
Prime Editing
CRISPR-Cas9
site-specific mutagenesis
transgenesis
Online Access:https://www.liebertpub.com/doi/full/10.1089/REGEN.2021.0016

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