Novel stromal biomarker screening in pancreatic cancer patients using the in vitro cancer-stromal interaction model

Novel stromal biomarker screening in pancreatic cancer patients using the in vitro cancer-stromal interaction model

Abstract Background Stromal fibroblasts associated with pancreatic ductal adenocarcinoma (PDAC) play an important role in tumor progression through interactions with cancer cells. Our proposed combination strategies of in vitro and in silico biomarker screening through a cancer-stromal interaction m...

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Bibliographic Details
Main Authors: Yasunori Nishida, Akiko Kawano Nagatsuma, Motohiro Kojima, Naoto Gotohda, Atsushi Ochiai
Format: Article
Language:English
Published: BMC 2020-12-01
Series:BMC Gastroenterology
Subjects:
Pancreatic cancer
Fibroblasts
Tumor microenvironment
Biomarkers
Online Access:https://doi.org/10.1186/s12876-020-01556-w

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