Adjunctive vitamin D therapy in various diseases in children: a scenario according to standard guideline
Abstract Background Adherence to standard guidelines is imperative when question comes to disease management. The present study aimed to evaluate the administration of adjunctive vitamin D therapy in various diseases, its adherence to standard guideline and the effect of socioeconomic status on the...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2022-05-01
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| Series: | BMC Pediatrics |
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| Online Access: | https://doi.org/10.1186/s12887-022-03297-z |
| _version_ | 1811307937202700288 |
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| author | Hafsa Arshad Faiz Ullah Khan Naveed Ahmed Naveed Anwer Ali Hassan Gillani Asim.ur. Rehman |
| author_facet | Hafsa Arshad Faiz Ullah Khan Naveed Ahmed Naveed Anwer Ali Hassan Gillani Asim.ur. Rehman |
| author_sort | Hafsa Arshad |
| collection | DOAJ |
| description | Abstract Background Adherence to standard guidelines is imperative when question comes to disease management. The present study aimed to evaluate the administration of adjunctive vitamin D therapy in various diseases, its adherence to standard guideline and the effect of socioeconomic status on the consumption of vitamin D in children. Methods Cross sectional observational study was conducted among 400 ambulatory pediatric patients at Children’s Hospital, Pakistan Institute of Medical Sciences Islamabad, from November 2017 to June 2018. Data were collected by a self-designed structured questionnaire from the patient’s medical chart. Adjunctive vitamin D therapy adherence was evaluated by the U. S endocrinology clinical practice guideline of vitamin D deficiency. The association between socioeconomic status and consumption of vitamin D was examined by chi-square. Alpha value (p ≤ 0.005) was considered statistically significant. Statistical analysis was done by SPSS version 25. Results In 400 patients, 9 diseases and 21 comorbid conditions were identified, in which adjunctive vitamin D therapy was prescribed. Adherence to vitamin D testing in high-risk vitamin D deficiency diseases as; seizures (3.8%), bone deformities (13.3%), steroid-resistant nephrotic syndrome (0.0%), cerebral palsy (5.9%) and meningitis (14.3%). Adherence to prescribed vitamin D dose was in (41.3%) patients in various diseases. Significant association (p < 0.05) was found between socioeconomic status and consumption of vitamin D in children and mothers. Conclusions It was found that adjunctive vitamin D was being prescribed in various diseases and comorbidities. Overall poor adherence to the standard guideline was observed in disease management in children. Low socioeconomic status affects vitamin D supplementation consumption in children. |
| first_indexed | 2024-04-13T09:13:14Z |
| format | Article |
| id | doaj.art-4187d0add2d94d86968464b73c16eef1 |
| institution | Directory Open Access Journal |
| issn | 1471-2431 |
| language | English |
| last_indexed | 2024-04-13T09:13:14Z |
| publishDate | 2022-05-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Pediatrics |
| spelling | doaj.art-4187d0add2d94d86968464b73c16eef12022-12-22T02:52:48ZengBMCBMC Pediatrics1471-24312022-05-0122111110.1186/s12887-022-03297-zAdjunctive vitamin D therapy in various diseases in children: a scenario according to standard guidelineHafsa Arshad0Faiz Ullah Khan1Naveed Ahmed2Naveed Anwer3Ali Hassan Gillani4Asim.ur. Rehman5Department of Pharmacy Quaid-i-Azam UniversityDepartment of Pharmacy Administration and Clinical Pharmacy, School of Pharmacy, Xi’an Jiaotong UniversityDepartment of Pharmacy Quaid-i-Azam UniversityDepartment of Pharmacy Quaid-i-Azam UniversityDepartment of Pharmacy Administration and Clinical Pharmacy, School of Pharmacy, Xi’an Jiaotong UniversityDepartment of Pharmacy Quaid-i-Azam UniversityAbstract Background Adherence to standard guidelines is imperative when question comes to disease management. The present study aimed to evaluate the administration of adjunctive vitamin D therapy in various diseases, its adherence to standard guideline and the effect of socioeconomic status on the consumption of vitamin D in children. Methods Cross sectional observational study was conducted among 400 ambulatory pediatric patients at Children’s Hospital, Pakistan Institute of Medical Sciences Islamabad, from November 2017 to June 2018. Data were collected by a self-designed structured questionnaire from the patient’s medical chart. Adjunctive vitamin D therapy adherence was evaluated by the U. S endocrinology clinical practice guideline of vitamin D deficiency. The association between socioeconomic status and consumption of vitamin D was examined by chi-square. Alpha value (p ≤ 0.005) was considered statistically significant. Statistical analysis was done by SPSS version 25. Results In 400 patients, 9 diseases and 21 comorbid conditions were identified, in which adjunctive vitamin D therapy was prescribed. Adherence to vitamin D testing in high-risk vitamin D deficiency diseases as; seizures (3.8%), bone deformities (13.3%), steroid-resistant nephrotic syndrome (0.0%), cerebral palsy (5.9%) and meningitis (14.3%). Adherence to prescribed vitamin D dose was in (41.3%) patients in various diseases. Significant association (p < 0.05) was found between socioeconomic status and consumption of vitamin D in children and mothers. Conclusions It was found that adjunctive vitamin D was being prescribed in various diseases and comorbidities. Overall poor adherence to the standard guideline was observed in disease management in children. Low socioeconomic status affects vitamin D supplementation consumption in children.https://doi.org/10.1186/s12887-022-03297-zAdjunctive vitamin D therapyGuideline adherenceSocioeconomic effectVitamin D supplementationComorbidities |
| spellingShingle | Hafsa Arshad Faiz Ullah Khan Naveed Ahmed Naveed Anwer Ali Hassan Gillani Asim.ur. Rehman Adjunctive vitamin D therapy in various diseases in children: a scenario according to standard guideline BMC Pediatrics Adjunctive vitamin D therapy Guideline adherence Socioeconomic effect Vitamin D supplementation Comorbidities |
| title | Adjunctive vitamin D therapy in various diseases in children: a scenario according to standard guideline |
| title_full | Adjunctive vitamin D therapy in various diseases in children: a scenario according to standard guideline |
| title_fullStr | Adjunctive vitamin D therapy in various diseases in children: a scenario according to standard guideline |
| title_full_unstemmed | Adjunctive vitamin D therapy in various diseases in children: a scenario according to standard guideline |
| title_short | Adjunctive vitamin D therapy in various diseases in children: a scenario according to standard guideline |
| title_sort | adjunctive vitamin d therapy in various diseases in children a scenario according to standard guideline |
| topic | Adjunctive vitamin D therapy Guideline adherence Socioeconomic effect Vitamin D supplementation Comorbidities |
| url | https://doi.org/10.1186/s12887-022-03297-z |
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