Pilot study of dogs with suppurative and non-suppurative Malassezia otitis: A case series
Abstract Background Rarely, Malassezia otitis presents as a painful, erosive otitis with an otic discharge containing Malassezia and neutrophils on cytology. There are no published reports of this type of suppurative Malassezia otitis (SMO). The role of Malassezia hypersensitivity in otitis is still...
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| Format: | Article |
| Language: | English |
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BMC
2021-11-01
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| Series: | BMC Veterinary Research |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12917-021-03066-7 |
| _version_ | 1831714937887522816 |
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| author | Tania C. Nunes Rodrigues Sophie I. Vandenabeele |
| author_facet | Tania C. Nunes Rodrigues Sophie I. Vandenabeele |
| author_sort | Tania C. Nunes Rodrigues |
| collection | DOAJ |
| description | Abstract Background Rarely, Malassezia otitis presents as a painful, erosive otitis with an otic discharge containing Malassezia and neutrophils on cytology. There are no published reports of this type of suppurative Malassezia otitis (SMO). The role of Malassezia hypersensitivity in otitis is still unknown, and no association has been demonstrated with SMO. We compared Malassezia IgE levels, intradermal test and histology changes in SMO dogs with the more conventional Malassezia otitis (MO) presentation. Results Three dogs (case 1, case 2 and case 3) were diagnosed with SMO, one dog (case 4) was diagnosed with unilateral MO and unilateral SMO, and one dog (case 5) was diagnosed with MO. Only one case (case 4) with SMO/MO had a positive Intradermal Allergy Test (IDAT) and elevated IgE levels for Malassezia. Histopathology findings from SMO revealed: interface dermatitis (case 1 and 3), lymphocytic dermatitis (case 2) and chronic hyperplastic eosinophilic and lymphoplasmacytic dermatitis (case 4). Histopathology findings from MO showed perivascular dermatitis (case 4 and 5). All the cases were treated successfully. Conclusions SMO presents with a distinct clinical phenotype in comparison with conventional MO. No consistent aetiology could be isolated. In these clinical cases it is possible that previous treatments could have influenced the results. More research is needed to understand the possible aetiologies and the pathogenesis of SMO. |
| first_indexed | 2024-12-21T00:09:43Z |
| format | Article |
| id | doaj.art-4187f175c99c4c678dcd2d5a70e83166 |
| institution | Directory Open Access Journal |
| issn | 1746-6148 |
| language | English |
| last_indexed | 2024-12-21T00:09:43Z |
| publishDate | 2021-11-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Veterinary Research |
| spelling | doaj.art-4187f175c99c4c678dcd2d5a70e831662022-12-21T19:22:22ZengBMCBMC Veterinary Research1746-61482021-11-011711710.1186/s12917-021-03066-7Pilot study of dogs with suppurative and non-suppurative Malassezia otitis: A case seriesTania C. Nunes Rodrigues0Sophie I. Vandenabeele1Small Animal Department, Faculty of Veterinary Medicine, Ghent UniversitySmall Animal Department, Faculty of Veterinary Medicine, Ghent UniversityAbstract Background Rarely, Malassezia otitis presents as a painful, erosive otitis with an otic discharge containing Malassezia and neutrophils on cytology. There are no published reports of this type of suppurative Malassezia otitis (SMO). The role of Malassezia hypersensitivity in otitis is still unknown, and no association has been demonstrated with SMO. We compared Malassezia IgE levels, intradermal test and histology changes in SMO dogs with the more conventional Malassezia otitis (MO) presentation. Results Three dogs (case 1, case 2 and case 3) were diagnosed with SMO, one dog (case 4) was diagnosed with unilateral MO and unilateral SMO, and one dog (case 5) was diagnosed with MO. Only one case (case 4) with SMO/MO had a positive Intradermal Allergy Test (IDAT) and elevated IgE levels for Malassezia. Histopathology findings from SMO revealed: interface dermatitis (case 1 and 3), lymphocytic dermatitis (case 2) and chronic hyperplastic eosinophilic and lymphoplasmacytic dermatitis (case 4). Histopathology findings from MO showed perivascular dermatitis (case 4 and 5). All the cases were treated successfully. Conclusions SMO presents with a distinct clinical phenotype in comparison with conventional MO. No consistent aetiology could be isolated. In these clinical cases it is possible that previous treatments could have influenced the results. More research is needed to understand the possible aetiologies and the pathogenesis of SMO.https://doi.org/10.1186/s12917-021-03066-7Malasseziahypersensitivitysuppurativeotitisinflammationcanine |
| spellingShingle | Tania C. Nunes Rodrigues Sophie I. Vandenabeele Pilot study of dogs with suppurative and non-suppurative Malassezia otitis: A case series BMC Veterinary Research Malassezia hypersensitivity suppurative otitis inflammation canine |
| title | Pilot study of dogs with suppurative and non-suppurative Malassezia otitis: A case series |
| title_full | Pilot study of dogs with suppurative and non-suppurative Malassezia otitis: A case series |
| title_fullStr | Pilot study of dogs with suppurative and non-suppurative Malassezia otitis: A case series |
| title_full_unstemmed | Pilot study of dogs with suppurative and non-suppurative Malassezia otitis: A case series |
| title_short | Pilot study of dogs with suppurative and non-suppurative Malassezia otitis: A case series |
| title_sort | pilot study of dogs with suppurative and non suppurative malassezia otitis a case series |
| topic | Malassezia hypersensitivity suppurative otitis inflammation canine |
| url | https://doi.org/10.1186/s12917-021-03066-7 |
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