Effect of weight loss on pregnancy outcomes, neuronal-reproductive-metabolic hormones and gene expression profiles in granulosa cells in obese infertile PCOS patients undergoing IVF-ET

Effect of weight loss on pregnancy outcomes, neuronal-reproductive-metabolic hormones and gene expression profiles in granulosa cells in obese infertile PCOS patients undergoing IVF-ET

ObjectiveTo investigate the effect of weight loss on pregnancy outcomes, PCOS related neuronal-reproductive-metabolic hormones and ovarian granulosa cell gene expression profiles in obese PCOS infertile patients undergoing in vitro fertilization-embryo transfer (IVF-ET).Methods75 patients undergoing...

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Bibliographic Details
Main Authors: Limin Wu, Qunying Fang, Mengli Wang, Yurui Wang, Xinyi Zhu, Zhaohui Fang, Fangting Lu, Bo Xu, Rentao Jin, Hui Han, Xianhong Tong
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Endocrinology
Subjects:
Polycystic ovary syndrome
weight loss
pregnancy outcome
neuronal-reproductive-metabolic hormones
granulosa cells
gene expression
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2022.954428/full

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https://www.frontiersin.org/articles/10.3389/fendo.2022.954428/full

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