Nanoparticulate Photoluminescent Probes for Bioimaging: Small Molecules and Polymers
Recent interest in research on photoluminescent molecules due to their unique properties has played an important role in advancing the bioimaging field. In particular, small molecules and organic dots as probes have great potential for the achievement of bioimaging because of their desirable propert...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-04-01
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| Series: | International Journal of Molecular Sciences |
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| Online Access: | https://www.mdpi.com/1422-0067/23/9/4949 |
| _version_ | 1797504481499283456 |
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| author | Sanghyuck Lee Chul Soon Park Hyeonseok Yoon |
| author_facet | Sanghyuck Lee Chul Soon Park Hyeonseok Yoon |
| author_sort | Sanghyuck Lee |
| collection | DOAJ |
| description | Recent interest in research on photoluminescent molecules due to their unique properties has played an important role in advancing the bioimaging field. In particular, small molecules and organic dots as probes have great potential for the achievement of bioimaging because of their desirable properties. In this review, we provide an introduction of probes consisting of fluorescent small molecules and polymers that emit light across the ultraviolet and near-infrared wavelength ranges, along with a brief summary of the most recent techniques for bioimaging. Since photoluminescence probes emitting light in different ranges have different goals and targets, their respective strategies also differ. Diverse and novel strategies using photoluminescence probes against targets have gradually been introduced in the related literature. Among recent papers (published within the last 5 years) on the topic, we here concentrate on the photophysical properties and strategies for the design of molecular probes, with key examples of in vivo photoluminescence research for practical applications. More in-depth studies on these probes will provide key insights into how to control the molecular structure and size/shape of organic probes for expanded bioimaging research and applications. |
| first_indexed | 2024-03-10T04:05:11Z |
| format | Article |
| id | doaj.art-418f0e3ca2264f68843a025724e249d5 |
| institution | Directory Open Access Journal |
| issn | 1661-6596 1422-0067 |
| language | English |
| last_indexed | 2024-03-10T04:05:11Z |
| publishDate | 2022-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | International Journal of Molecular Sciences |
| spelling | doaj.art-418f0e3ca2264f68843a025724e249d52023-11-23T08:24:39ZengMDPI AGInternational Journal of Molecular Sciences1661-65961422-00672022-04-01239494910.3390/ijms23094949Nanoparticulate Photoluminescent Probes for Bioimaging: Small Molecules and PolymersSanghyuck Lee0Chul Soon Park1Hyeonseok Yoon2Department of Polymer Engineering, Graduate School, Chonnam National University, 77 Yongbong-ro, Buk-gu, Gwangju 61186, KoreaDrug Manufacturing Center, Daegu-Gyeongbuk Medical Innovation Foundation (DGMIF), Daegu 41061, KoreaDepartment of Polymer Engineering, Graduate School, Chonnam National University, 77 Yongbong-ro, Buk-gu, Gwangju 61186, KoreaRecent interest in research on photoluminescent molecules due to their unique properties has played an important role in advancing the bioimaging field. In particular, small molecules and organic dots as probes have great potential for the achievement of bioimaging because of their desirable properties. In this review, we provide an introduction of probes consisting of fluorescent small molecules and polymers that emit light across the ultraviolet and near-infrared wavelength ranges, along with a brief summary of the most recent techniques for bioimaging. Since photoluminescence probes emitting light in different ranges have different goals and targets, their respective strategies also differ. Diverse and novel strategies using photoluminescence probes against targets have gradually been introduced in the related literature. Among recent papers (published within the last 5 years) on the topic, we here concentrate on the photophysical properties and strategies for the design of molecular probes, with key examples of in vivo photoluminescence research for practical applications. More in-depth studies on these probes will provide key insights into how to control the molecular structure and size/shape of organic probes for expanded bioimaging research and applications.https://www.mdpi.com/1422-0067/23/9/4949photoluminescencebioimagingpolymer dotsnear-infraredquantum dotssmall-molecule probes |
| spellingShingle | Sanghyuck Lee Chul Soon Park Hyeonseok Yoon Nanoparticulate Photoluminescent Probes for Bioimaging: Small Molecules and Polymers International Journal of Molecular Sciences photoluminescence bioimaging polymer dots near-infrared quantum dots small-molecule probes |
| title | Nanoparticulate Photoluminescent Probes for Bioimaging: Small Molecules and Polymers |
| title_full | Nanoparticulate Photoluminescent Probes for Bioimaging: Small Molecules and Polymers |
| title_fullStr | Nanoparticulate Photoluminescent Probes for Bioimaging: Small Molecules and Polymers |
| title_full_unstemmed | Nanoparticulate Photoluminescent Probes for Bioimaging: Small Molecules and Polymers |
| title_short | Nanoparticulate Photoluminescent Probes for Bioimaging: Small Molecules and Polymers |
| title_sort | nanoparticulate photoluminescent probes for bioimaging small molecules and polymers |
| topic | photoluminescence bioimaging polymer dots near-infrared quantum dots small-molecule probes |
| url | https://www.mdpi.com/1422-0067/23/9/4949 |
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