Patient weight has diverse effects on the prescribing of different antibiotics to dogs
IntroductionVarious factors including body weight-associated treatment cost may influence the probability of dispensing antibiotics to dogs in first-opinion practice, but their effect on specific drug choice remains unclear.MethodsMultiple membership regression modeling was used to investigate the p...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2024-02-01
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| Series: | Frontiers in Veterinary Science |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fvets.2024.1358535/full |
| _version_ | 1797303377635311616 |
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| author | Stuart D. Becker Stuart D. Becker David M. Hughes |
| author_facet | Stuart D. Becker Stuart D. Becker David M. Hughes |
| author_sort | Stuart D. Becker |
| collection | DOAJ |
| description | IntroductionVarious factors including body weight-associated treatment cost may influence the probability of dispensing antibiotics to dogs in first-opinion practice, but their effect on specific drug choice remains unclear.MethodsMultiple membership regression modeling was used to investigate the probability of dispensing 12 different antibiotics to dogs of different weights in the context of various disease presentations, using anonymized data obtained from electronic health records of 18 clinics between 2020 and 2022. Data from 14,259 dogs were analyzed.ResultsTreatment choice varied significantly with animal weight. Higher body weight was associated with an increased likelihood of dispensing lower cost antimicrobials such as amoxicillin and trimethoprim sulfonamide, while use of higher cost antimicrobials such as cefovecin was strongly biased to smaller animals. However, these effects were limited when restricted treatment options were available for the target condition.ConclusionThis work demonstrates that anticipated financial costs may result in different treatment choices for canine patients depending on their body weight. Further work is needed to understand the impact of financial pressures on veterinarians’ treatment choices, and the implications for the optimization of antimicrobial stewardship in first opinion practice. |
| first_indexed | 2024-03-07T23:51:52Z |
| format | Article |
| id | doaj.art-418f9bb74e964c159ee48d7fd17e96f1 |
| institution | Directory Open Access Journal |
| issn | 2297-1769 |
| language | English |
| last_indexed | 2024-03-07T23:51:52Z |
| publishDate | 2024-02-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Veterinary Science |
| spelling | doaj.art-418f9bb74e964c159ee48d7fd17e96f12024-02-19T04:34:58ZengFrontiers Media S.A.Frontiers in Veterinary Science2297-17692024-02-011110.3389/fvets.2024.13585351358535Patient weight has diverse effects on the prescribing of different antibiotics to dogsStuart D. Becker0Stuart D. Becker1David M. Hughes2Department of Health Data Science, Institute of Population Health, University of Liverpool, Liverpool, United KingdomPathobiology and Population Sciences, The Royal Veterinary College, Hertfordshire, United KingdomDepartment of Health Data Science, Institute of Population Health, University of Liverpool, Liverpool, United KingdomIntroductionVarious factors including body weight-associated treatment cost may influence the probability of dispensing antibiotics to dogs in first-opinion practice, but their effect on specific drug choice remains unclear.MethodsMultiple membership regression modeling was used to investigate the probability of dispensing 12 different antibiotics to dogs of different weights in the context of various disease presentations, using anonymized data obtained from electronic health records of 18 clinics between 2020 and 2022. Data from 14,259 dogs were analyzed.ResultsTreatment choice varied significantly with animal weight. Higher body weight was associated with an increased likelihood of dispensing lower cost antimicrobials such as amoxicillin and trimethoprim sulfonamide, while use of higher cost antimicrobials such as cefovecin was strongly biased to smaller animals. However, these effects were limited when restricted treatment options were available for the target condition.ConclusionThis work demonstrates that anticipated financial costs may result in different treatment choices for canine patients depending on their body weight. Further work is needed to understand the impact of financial pressures on veterinarians’ treatment choices, and the implications for the optimization of antimicrobial stewardship in first opinion practice.https://www.frontiersin.org/articles/10.3389/fvets.2024.1358535/fullantibioticantimicrobial stewardshipcaninecosttreatment choiceveterinary |
| spellingShingle | Stuart D. Becker Stuart D. Becker David M. Hughes Patient weight has diverse effects on the prescribing of different antibiotics to dogs Frontiers in Veterinary Science antibiotic antimicrobial stewardship canine cost treatment choice veterinary |
| title | Patient weight has diverse effects on the prescribing of different antibiotics to dogs |
| title_full | Patient weight has diverse effects on the prescribing of different antibiotics to dogs |
| title_fullStr | Patient weight has diverse effects on the prescribing of different antibiotics to dogs |
| title_full_unstemmed | Patient weight has diverse effects on the prescribing of different antibiotics to dogs |
| title_short | Patient weight has diverse effects on the prescribing of different antibiotics to dogs |
| title_sort | patient weight has diverse effects on the prescribing of different antibiotics to dogs |
| topic | antibiotic antimicrobial stewardship canine cost treatment choice veterinary |
| url | https://www.frontiersin.org/articles/10.3389/fvets.2024.1358535/full |
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