Bayesian linkage analysis of categorical traits for arbitrary pedigree designs.

Bayesian linkage analysis of categorical traits for arbitrary pedigree designs.

Pedigree studies of complex heritable diseases often feature nominal or ordinal phenotypic measurements and missing genetic marker or phenotype data.We have developed a Bayesian method for Linkage analysis of Ordinal and Categorical traits (LOCate) that can analyze complex genealogical structure for...

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Bibliographic Details
Main Authors: Abra Brisbin, Myrna M Weissman, Abby J Fyer, Steven P Hamilton, James A Knowles, Carlos D Bustamante, Jason G Mezey
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-08-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2928726?pdf=render

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