Transmission of Methicillin-Resistant <i>Staphylococcus</i> spp. from Infected Dogs to the Home Environment and Owners
Dogs with methicillin-resistant <i>Staphylococcus</i> spp. (MRS) infections often undergo treatment in their homes, interacting with their owners and surroundings. This close contact between dogs and owners may facilitate the interspecies transmission of MRS. Therefore, this study aimed...
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| Format: | Article |
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MDPI AG
2022-05-01
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| Series: | Antibiotics |
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| Online Access: | https://www.mdpi.com/2079-6382/11/5/637 |
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| author | Mari Røken Stanislav Iakhno Anita Haug Haaland Yngvild Wasteson Ane Mohn Bjelland |
| author_facet | Mari Røken Stanislav Iakhno Anita Haug Haaland Yngvild Wasteson Ane Mohn Bjelland |
| author_sort | Mari Røken |
| collection | DOAJ |
| description | Dogs with methicillin-resistant <i>Staphylococcus</i> spp. (MRS) infections often undergo treatment in their homes, interacting with their owners and surroundings. This close contact between dogs and owners may facilitate the interspecies transmission of MRS. Therefore, this study aimed to investigate the transmission of MRS from infected dogs to their owners and home environments. Seven households with dogs that had been diagnosed with methicillin-resistant <i>S. pseudintermedius</i> (MRSP) and one household with a dog with methicillin-resistant <i>S. epidermidis</i> (MRSE) participated in the study. Dogs, owners, and the home environments were screened for the presence of clinical MRS. A selection of 36 staphylococcal isolates were whole-genome sequenced and screened for resistance genes and virulence genes. Clinical MRS were primarily identified from the dogs and their immediate surroundings, but these were also detected in locations that were out of reach for the dogs, indicating indirect transmission. Two of eight owners carried clinical MRS in their nostrils, while one owner carried methicillin-susceptible <i>S. pseudintermedius</i> (MSSP). All clinical MRS were multi-resistant, and several possessed resistance genes that were not expressed phenotypically. Clinical MRSP persisted in the home environment for a prolonged period, despite infection recovery and one dog being euthanized. Regardless of the stable presence of MRSP in the surroundings, the owners in these homes remained negative, but tested positive for MSSP on three occasions. |
| first_indexed | 2024-03-10T03:27:10Z |
| format | Article |
| id | doaj.art-4191d50fe79c4b95a7f22b9204b828fb |
| institution | Directory Open Access Journal |
| issn | 2079-6382 |
| language | English |
| last_indexed | 2024-03-10T03:27:10Z |
| publishDate | 2022-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Antibiotics |
| spelling | doaj.art-4191d50fe79c4b95a7f22b9204b828fb2023-11-23T09:48:57ZengMDPI AGAntibiotics2079-63822022-05-0111563710.3390/antibiotics11050637Transmission of Methicillin-Resistant <i>Staphylococcus</i> spp. from Infected Dogs to the Home Environment and OwnersMari Røken0Stanislav Iakhno1Anita Haug Haaland2Yngvild Wasteson3Ane Mohn Bjelland4Department of Paraclinical Sciences, Faculty of Veterinary Medicine, Norwegian University of Life Sciences, 1433 Ås, NorwayResearch and Development, Previwo AS, 0454 Oslo, NorwayDepartment of Companion Animal Clinical Sciences, Faculty of Veterinary Medicine, Norwegian University of Life Sciences, 1433 Ås, NorwayDepartment of Paraclinical Sciences, Faculty of Veterinary Medicine, Norwegian University of Life Sciences, 1433 Ås, NorwayDepartment of Paraclinical Sciences, Faculty of Veterinary Medicine, Norwegian University of Life Sciences, 1433 Ås, NorwayDogs with methicillin-resistant <i>Staphylococcus</i> spp. (MRS) infections often undergo treatment in their homes, interacting with their owners and surroundings. This close contact between dogs and owners may facilitate the interspecies transmission of MRS. Therefore, this study aimed to investigate the transmission of MRS from infected dogs to their owners and home environments. Seven households with dogs that had been diagnosed with methicillin-resistant <i>S. pseudintermedius</i> (MRSP) and one household with a dog with methicillin-resistant <i>S. epidermidis</i> (MRSE) participated in the study. Dogs, owners, and the home environments were screened for the presence of clinical MRS. A selection of 36 staphylococcal isolates were whole-genome sequenced and screened for resistance genes and virulence genes. Clinical MRS were primarily identified from the dogs and their immediate surroundings, but these were also detected in locations that were out of reach for the dogs, indicating indirect transmission. Two of eight owners carried clinical MRS in their nostrils, while one owner carried methicillin-susceptible <i>S. pseudintermedius</i> (MSSP). All clinical MRS were multi-resistant, and several possessed resistance genes that were not expressed phenotypically. Clinical MRSP persisted in the home environment for a prolonged period, despite infection recovery and one dog being euthanized. Regardless of the stable presence of MRSP in the surroundings, the owners in these homes remained negative, but tested positive for MSSP on three occasions.https://www.mdpi.com/2079-6382/11/5/637antimicrobial resistancemethicillin-resistanceone health<i>Staphylococcus pseudintermedius</i><i>Staphylococcus epidermidis</i> |
| spellingShingle | Mari Røken Stanislav Iakhno Anita Haug Haaland Yngvild Wasteson Ane Mohn Bjelland Transmission of Methicillin-Resistant <i>Staphylococcus</i> spp. from Infected Dogs to the Home Environment and Owners Antibiotics antimicrobial resistance methicillin-resistance one health <i>Staphylococcus pseudintermedius</i> <i>Staphylococcus epidermidis</i> |
| title | Transmission of Methicillin-Resistant <i>Staphylococcus</i> spp. from Infected Dogs to the Home Environment and Owners |
| title_full | Transmission of Methicillin-Resistant <i>Staphylococcus</i> spp. from Infected Dogs to the Home Environment and Owners |
| title_fullStr | Transmission of Methicillin-Resistant <i>Staphylococcus</i> spp. from Infected Dogs to the Home Environment and Owners |
| title_full_unstemmed | Transmission of Methicillin-Resistant <i>Staphylococcus</i> spp. from Infected Dogs to the Home Environment and Owners |
| title_short | Transmission of Methicillin-Resistant <i>Staphylococcus</i> spp. from Infected Dogs to the Home Environment and Owners |
| title_sort | transmission of methicillin resistant i staphylococcus i spp from infected dogs to the home environment and owners |
| topic | antimicrobial resistance methicillin-resistance one health <i>Staphylococcus pseudintermedius</i> <i>Staphylococcus epidermidis</i> |
| url | https://www.mdpi.com/2079-6382/11/5/637 |
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