Polyaryletherketones: Properties and applications in modern medicine

Polyaryletherketones (PAEKs) are a family of durable, multifunctional, thermoplastic biopolymers. This article first provides necessary context and thorough information regarding the mechanical, physical, chemical, crystalline, and shape memory properties of PAEKs as well as critical details regardi...

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Main Authors: Gregory Sacks, Veer Shah, Lilian Yao, Catherine Yan, Darshi Shah, Lorely Limeta, Vincent DeStefano
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2024-06-01
Series:Biomedical Technology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2949723X23000673
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author Gregory Sacks
Veer Shah
Lilian Yao
Catherine Yan
Darshi Shah
Lorely Limeta
Vincent DeStefano
author_facet Gregory Sacks
Veer Shah
Lilian Yao
Catherine Yan
Darshi Shah
Lorely Limeta
Vincent DeStefano
author_sort Gregory Sacks
collection DOAJ
description Polyaryletherketones (PAEKs) are a family of durable, multifunctional, thermoplastic biopolymers. This article first provides necessary context and thorough information regarding the mechanical, physical, chemical, crystalline, and shape memory properties of PAEKs as well as critical details regarding manufacturing. Additionally, it provides an update on the clinical and biomedical uses of PAEKs by summarizing the most recent and groundbreaking applications of these thermopolymers. PAEKs have been used clinically in fields including orthopedics, craniofacial and cardiothoracic surgery, as well as cardiovascular and dental medicine. Other applications include tissue engineering, post-surgical antibiotic delivery, antimicrobial applications, anti-cancer drug delivery, and 3D printing. Of importance, PAEKs have comparable mechanical strength and elastic modulus to human bone, which enable PAEKs to serve as a viable alternative to metal-based implants. Given their remarkable properties, and ability to be specifically and rapidly manufactured through 3D printing, PAEKs will continue to be a subject of biomedical research and serve a vital role in medical applications.
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spelling doaj.art-4191fbf6f35a45eaa54926dc6c0316842024-01-10T04:39:35ZengKeAi Communications Co., Ltd.Biomedical Technology2949-723X2024-06-0167589Polyaryletherketones: Properties and applications in modern medicineGregory Sacks0Veer Shah1Lilian Yao2Catherine Yan3Darshi Shah4Lorely Limeta5Vincent DeStefano6Renaissance School of Medicine at Stony Brook University, Stony Brook, NY, USADepartment of Mechanical and Industrial Engineering, Northeastern University, Boston, MA, USAStanford University, Stanford, CA, USARenaissance School of Medicine at Stony Brook University, Stony Brook, NY, USARenaissance School of Medicine at Stony Brook University, Stony Brook, NY, USAStony Brook University, Stony Brook, NY, USARenaissance School of Medicine at Stony Brook University, Stony Brook, NY, USA; Corresponding author.Polyaryletherketones (PAEKs) are a family of durable, multifunctional, thermoplastic biopolymers. This article first provides necessary context and thorough information regarding the mechanical, physical, chemical, crystalline, and shape memory properties of PAEKs as well as critical details regarding manufacturing. Additionally, it provides an update on the clinical and biomedical uses of PAEKs by summarizing the most recent and groundbreaking applications of these thermopolymers. PAEKs have been used clinically in fields including orthopedics, craniofacial and cardiothoracic surgery, as well as cardiovascular and dental medicine. Other applications include tissue engineering, post-surgical antibiotic delivery, antimicrobial applications, anti-cancer drug delivery, and 3D printing. Of importance, PAEKs have comparable mechanical strength and elastic modulus to human bone, which enable PAEKs to serve as a viable alternative to metal-based implants. Given their remarkable properties, and ability to be specifically and rapidly manufactured through 3D printing, PAEKs will continue to be a subject of biomedical research and serve a vital role in medical applications.http://www.sciencedirect.com/science/article/pii/S2949723X23000673PolyetheretherketonePolyetherketoneketoneTissue engineeringOrthopedicsSpine
spellingShingle Gregory Sacks
Veer Shah
Lilian Yao
Catherine Yan
Darshi Shah
Lorely Limeta
Vincent DeStefano
Polyaryletherketones: Properties and applications in modern medicine
Biomedical Technology
Polyetheretherketone
Polyetherketoneketone
Tissue engineering
Orthopedics
Spine
title Polyaryletherketones: Properties and applications in modern medicine
title_full Polyaryletherketones: Properties and applications in modern medicine
title_fullStr Polyaryletherketones: Properties and applications in modern medicine
title_full_unstemmed Polyaryletherketones: Properties and applications in modern medicine
title_short Polyaryletherketones: Properties and applications in modern medicine
title_sort polyaryletherketones properties and applications in modern medicine
topic Polyetheretherketone
Polyetherketoneketone
Tissue engineering
Orthopedics
Spine
url http://www.sciencedirect.com/science/article/pii/S2949723X23000673
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