Novel Method of Classification in Knee Osteoarthritis: Machine Learning Application Versus Logistic Regression Model

Objective To present new classification methods of knee osteoarthritis (KOA) using machine learning and compare its performance with conventional statistical methods as classification techniques using machine learning have recently been developed. Methods A total of 84 KOA patients and 97 normal par...

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Main Authors: Jung Ho Yang, Jae Hyeon Park, Seong-Ho Jang, Jaesung Cho
Format: Article
Language:English
Published: Korean Academy of Rehabilitation Medicine 2020-12-01
Series:Annals of Rehabilitation Medicine
Subjects:
Online Access:http://www.e-arm.org/upload/pdf/arm-20071.pdf
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author Jung Ho Yang
Jae Hyeon Park
Seong-Ho Jang
Jaesung Cho
author_facet Jung Ho Yang
Jae Hyeon Park
Seong-Ho Jang
Jaesung Cho
author_sort Jung Ho Yang
collection DOAJ
description Objective To present new classification methods of knee osteoarthritis (KOA) using machine learning and compare its performance with conventional statistical methods as classification techniques using machine learning have recently been developed. Methods A total of 84 KOA patients and 97 normal participants were recruited. KOA patients were clustered into three groups according to the Kellgren-Lawrence (K-L) grading system. All subjects completed gait trials under the same experimental conditions. Machine learning-based classification using the support vector machine (SVM) classifier was performed to classify KOA patients and the severity of KOA. Logistic regression analysis was also performed to compare the results in classifying KOA patients with machine learning method. Results In the classification between KOA patients and normal subjects, the accuracy of classification was higher in machine learning method than in logistic regression analysis. In the classification of KOA severity, accuracy was enhanced through the feature selection process in the machine learning method. The most significant gait feature for classification was flexion and extension of the knee in the swing phase in the machine learning method. Conclusion The machine learning method is thought to be a new approach to complement conventional logistic regression analysis in the classification of KOA patients. It can be clinically used for diagnosis and gait correction of KOA patients.
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spelling doaj.art-4192d7bb1a3443489bb2b439cca48a2a2023-09-03T03:15:24ZengKorean Academy of Rehabilitation MedicineAnnals of Rehabilitation Medicine2234-06452234-06532020-12-0144641542710.5535/arm.200714186Novel Method of Classification in Knee Osteoarthritis: Machine Learning Application Versus Logistic Regression ModelJung Ho Yang0Jae Hyeon Park1Seong-Ho Jang2Jaesung Cho3 Department of Rehabilitation Medicine, Hanyang University College of Medicine, Seoul, Korea Department of Rehabilitation Medicine, Hanyang University Guri Hospital, Hanyang University College of Medicine, Guri, Korea Department of Rehabilitation Medicine, Hanyang University College of Medicine, Seoul, Korea Korea Orthopedics & Rehabilitation Engineering Center, Incheon, KoreaObjective To present new classification methods of knee osteoarthritis (KOA) using machine learning and compare its performance with conventional statistical methods as classification techniques using machine learning have recently been developed. Methods A total of 84 KOA patients and 97 normal participants were recruited. KOA patients were clustered into three groups according to the Kellgren-Lawrence (K-L) grading system. All subjects completed gait trials under the same experimental conditions. Machine learning-based classification using the support vector machine (SVM) classifier was performed to classify KOA patients and the severity of KOA. Logistic regression analysis was also performed to compare the results in classifying KOA patients with machine learning method. Results In the classification between KOA patients and normal subjects, the accuracy of classification was higher in machine learning method than in logistic regression analysis. In the classification of KOA severity, accuracy was enhanced through the feature selection process in the machine learning method. The most significant gait feature for classification was flexion and extension of the knee in the swing phase in the machine learning method. Conclusion The machine learning method is thought to be a new approach to complement conventional logistic regression analysis in the classification of KOA patients. It can be clinically used for diagnosis and gait correction of KOA patients.http://www.e-arm.org/upload/pdf/arm-20071.pdfknee osteoarthritisgait analysisknee jointseveritymachine learning
spellingShingle Jung Ho Yang
Jae Hyeon Park
Seong-Ho Jang
Jaesung Cho
Novel Method of Classification in Knee Osteoarthritis: Machine Learning Application Versus Logistic Regression Model
Annals of Rehabilitation Medicine
knee osteoarthritis
gait analysis
knee joint
severity
machine learning
title Novel Method of Classification in Knee Osteoarthritis: Machine Learning Application Versus Logistic Regression Model
title_full Novel Method of Classification in Knee Osteoarthritis: Machine Learning Application Versus Logistic Regression Model
title_fullStr Novel Method of Classification in Knee Osteoarthritis: Machine Learning Application Versus Logistic Regression Model
title_full_unstemmed Novel Method of Classification in Knee Osteoarthritis: Machine Learning Application Versus Logistic Regression Model
title_short Novel Method of Classification in Knee Osteoarthritis: Machine Learning Application Versus Logistic Regression Model
title_sort novel method of classification in knee osteoarthritis machine learning application versus logistic regression model
topic knee osteoarthritis
gait analysis
knee joint
severity
machine learning
url http://www.e-arm.org/upload/pdf/arm-20071.pdf
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AT jaehyeonpark novelmethodofclassificationinkneeosteoarthritismachinelearningapplicationversuslogisticregressionmodel
AT seonghojang novelmethodofclassificationinkneeosteoarthritismachinelearningapplicationversuslogisticregressionmodel
AT jaesungcho novelmethodofclassificationinkneeosteoarthritismachinelearningapplicationversuslogisticregressionmodel