The porcine Major Histocompatibility Complex and related paralogous regions: a review
<p>Abstract</p> <p>The physical alignment of the entire region of the pig major histocompatibility complex (MHC) has been almost completed. In swine, the MHC is called the SLA (swine leukocyte antigen) and most of its class I region has been sequenced. Over one hundred genes have b...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | deu |
| Published: |
BMC
2000-03-01
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| Series: | Genetics Selection Evolution |
| Subjects: | |
| Online Access: | http://www.gsejournal.org/content/32/2/109 |
| _version_ | 1818688754259329024 |
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| author | Vaiman Marcel Gaillard Claire Renard Christine Chardon Patrick |
| author_facet | Vaiman Marcel Gaillard Claire Renard Christine Chardon Patrick |
| author_sort | Vaiman Marcel |
| collection | DOAJ |
| description | <p>Abstract</p> <p>The physical alignment of the entire region of the pig major histocompatibility complex (MHC) has been almost completed. In swine, the MHC is called the SLA (swine leukocyte antigen) and most of its class I region has been sequenced. Over one hundred genes have been characterised, including the classical class I and class I-related genes, as well as the class II gene families. These results in swine provide new evidence for the striking conservation during the evolution of a general MHC framework, and are consistent with the location of the class I genes on segments referred to as permissive places within the MHC class I region. Recent results confirm the involvement of the SLA region in numerous quantitative traits.</p> |
| first_indexed | 2024-12-17T11:59:14Z |
| format | Article |
| id | doaj.art-4197830fdf8943e089ca46fea8c26bd6 |
| institution | Directory Open Access Journal |
| issn | 0999-193X 1297-9686 |
| language | deu |
| last_indexed | 2024-12-17T11:59:14Z |
| publishDate | 2000-03-01 |
| publisher | BMC |
| record_format | Article |
| series | Genetics Selection Evolution |
| spelling | doaj.art-4197830fdf8943e089ca46fea8c26bd62022-12-21T21:49:54ZdeuBMCGenetics Selection Evolution0999-193X1297-96862000-03-0132210912810.1186/1297-9686-32-2-109The porcine Major Histocompatibility Complex and related paralogous regions: a reviewVaiman MarcelGaillard ClaireRenard ChristineChardon Patrick<p>Abstract</p> <p>The physical alignment of the entire region of the pig major histocompatibility complex (MHC) has been almost completed. In swine, the MHC is called the SLA (swine leukocyte antigen) and most of its class I region has been sequenced. Over one hundred genes have been characterised, including the classical class I and class I-related genes, as well as the class II gene families. These results in swine provide new evidence for the striking conservation during the evolution of a general MHC framework, and are consistent with the location of the class I genes on segments referred to as permissive places within the MHC class I region. Recent results confirm the involvement of the SLA region in numerous quantitative traits.</p>http://www.gsejournal.org/content/32/2/109pigmajor histocompatibility complexphysical mapperformanceparalogous regions |
| spellingShingle | Vaiman Marcel Gaillard Claire Renard Christine Chardon Patrick The porcine Major Histocompatibility Complex and related paralogous regions: a review Genetics Selection Evolution pig major histocompatibility complex physical map performance paralogous regions |
| title | The porcine Major Histocompatibility Complex and related paralogous regions: a review |
| title_full | The porcine Major Histocompatibility Complex and related paralogous regions: a review |
| title_fullStr | The porcine Major Histocompatibility Complex and related paralogous regions: a review |
| title_full_unstemmed | The porcine Major Histocompatibility Complex and related paralogous regions: a review |
| title_short | The porcine Major Histocompatibility Complex and related paralogous regions: a review |
| title_sort | porcine major histocompatibility complex and related paralogous regions a review |
| topic | pig major histocompatibility complex physical map performance paralogous regions |
| url | http://www.gsejournal.org/content/32/2/109 |
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