Erythropoietin, Vitamin D3 and Parathormone level associated with kidney lesions in buffalo (Bubalus bubalis)
Many diseases, including renal disorders in ruminants, appear in subclinical form and lead to reduced production without causing clinical signs. In this research, blood and tissue samples of kidney were taken from 102 buffaloes from Ahvaz industrial abattoir and sent to the laboratory for biochemica...
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| Format: | Article |
| Language: | English |
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Ferdowsi University of Mashhad
2020-06-01
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| Series: | The Iranian Journal of Veterinary Science and Technology |
| Subjects: | |
| Online Access: | https://ijvst.um.ac.ir/article_30863_2f606a7ae61d216dbb06ca19d23e9a2c.pdf |
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| author | Zana Shahabi Mohammad Razi Jalali Babak Mohamadian Mohammad Rahim Haji Hajikolaei Mohammad Taha Jalali |
| author_facet | Zana Shahabi Mohammad Razi Jalali Babak Mohamadian Mohammad Rahim Haji Hajikolaei Mohammad Taha Jalali |
| author_sort | Zana Shahabi |
| collection | DOAJ |
| description | Many diseases, including renal disorders in ruminants, appear in subclinical form and lead to reduced production without causing clinical signs. In this research, blood and tissue samples of kidney were taken from 102 buffaloes from Ahvaz industrial abattoir and sent to the laboratory for biochemical and histopathological analysis. After preparing the pathological sections from kidney specimens, conventional and specific staining and microscopic examination, 41 samples had no kidney lesion was considered as control and 61 specimens as the lesion group. The samples with renal lesions were divided into 4 subgroups including acute tubulointerstitial nephritis, chronic tubulointerstitial nephritis, Urinary tubular inflammation, and Congestion. The samples were also divided and compared to males and females. In blood samples, serum biochemical tests including parathyroid hormone, erythropoietin, and vitamin D3 were measured by using ELISA-specific commercial kits. After statistical analysis, the results of vitamin D3 in the studied groups did not show any significant difference. However, erythropoietin and parathormone values in buffaloes with renal lesions were significantly lower and higher than those in control animals respectively. The results of this study showed that most of the kidney lesions in the studied buffaloes including the mentioned above have led to a decrease in the production of erythropoietin hormone following the occurrence of these lesions and its functional effects on the kidneys. Naturally, the effects of this hormone deficiency are expected to be reflected in the hemogram and eventually, anemia resulting from it may affect overall body health. |
| first_indexed | 2024-12-19T12:14:50Z |
| format | Article |
| id | doaj.art-4197ed57b7764b8f9c755812e1d48102 |
| institution | Directory Open Access Journal |
| issn | 2008-465X 2423-6306 |
| language | English |
| last_indexed | 2024-12-19T12:14:50Z |
| publishDate | 2020-06-01 |
| publisher | Ferdowsi University of Mashhad |
| record_format | Article |
| series | The Iranian Journal of Veterinary Science and Technology |
| spelling | doaj.art-4197ed57b7764b8f9c755812e1d481022022-12-21T20:22:01ZengFerdowsi University of MashhadThe Iranian Journal of Veterinary Science and Technology2008-465X2423-63062020-06-01121293610.22067/veterinary.v12i1.8531330863Erythropoietin, Vitamin D3 and Parathormone level associated with kidney lesions in buffalo (Bubalus bubalis)Zana Shahabi0Mohammad Razi Jalali1Babak Mohamadian2Mohammad Rahim Haji Hajikolaei3Mohammad Taha Jalali4DVSc Student of Clinical PathologyShahid Chamran University of AhvazFaculty of Veterinary Medicine, Shahid Chamran University of AhvazFaculty of Veterinary Medicine, Shahid Chamran University of Ahvaz, Ahvaz, IranFaculty of Para Medical Sciences, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IranMany diseases, including renal disorders in ruminants, appear in subclinical form and lead to reduced production without causing clinical signs. In this research, blood and tissue samples of kidney were taken from 102 buffaloes from Ahvaz industrial abattoir and sent to the laboratory for biochemical and histopathological analysis. After preparing the pathological sections from kidney specimens, conventional and specific staining and microscopic examination, 41 samples had no kidney lesion was considered as control and 61 specimens as the lesion group. The samples with renal lesions were divided into 4 subgroups including acute tubulointerstitial nephritis, chronic tubulointerstitial nephritis, Urinary tubular inflammation, and Congestion. The samples were also divided and compared to males and females. In blood samples, serum biochemical tests including parathyroid hormone, erythropoietin, and vitamin D3 were measured by using ELISA-specific commercial kits. After statistical analysis, the results of vitamin D3 in the studied groups did not show any significant difference. However, erythropoietin and parathormone values in buffaloes with renal lesions were significantly lower and higher than those in control animals respectively. The results of this study showed that most of the kidney lesions in the studied buffaloes including the mentioned above have led to a decrease in the production of erythropoietin hormone following the occurrence of these lesions and its functional effects on the kidneys. Naturally, the effects of this hormone deficiency are expected to be reflected in the hemogram and eventually, anemia resulting from it may affect overall body health.https://ijvst.um.ac.ir/article_30863_2f606a7ae61d216dbb06ca19d23e9a2c.pdfbubalus bubaliskidney lesionserythropoietinvitamin d3parathormone |
| spellingShingle | Zana Shahabi Mohammad Razi Jalali Babak Mohamadian Mohammad Rahim Haji Hajikolaei Mohammad Taha Jalali Erythropoietin, Vitamin D3 and Parathormone level associated with kidney lesions in buffalo (Bubalus bubalis) The Iranian Journal of Veterinary Science and Technology bubalus bubalis kidney lesions erythropoietin vitamin d3 parathormone |
| title | Erythropoietin, Vitamin D3 and Parathormone level associated with kidney lesions in buffalo (Bubalus bubalis) |
| title_full | Erythropoietin, Vitamin D3 and Parathormone level associated with kidney lesions in buffalo (Bubalus bubalis) |
| title_fullStr | Erythropoietin, Vitamin D3 and Parathormone level associated with kidney lesions in buffalo (Bubalus bubalis) |
| title_full_unstemmed | Erythropoietin, Vitamin D3 and Parathormone level associated with kidney lesions in buffalo (Bubalus bubalis) |
| title_short | Erythropoietin, Vitamin D3 and Parathormone level associated with kidney lesions in buffalo (Bubalus bubalis) |
| title_sort | erythropoietin vitamin d3 and parathormone level associated with kidney lesions in buffalo bubalus bubalis |
| topic | bubalus bubalis kidney lesions erythropoietin vitamin d3 parathormone |
| url | https://ijvst.um.ac.ir/article_30863_2f606a7ae61d216dbb06ca19d23e9a2c.pdf |
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