An East-Asian-type cagA Helicobacter pylori Infected Patient with Clinical Manifestation Gastric Ulcer
We reported a male, 72 yo, Chinese ethnic with chief complaint black mushy defecation. Physical examination revealed pale on conjunctival palpebra which confirmed as anemia on complete blood count. Gastroduodenoscopy revealed a 3 mm ulcer at the antrum (Forrest stage III). H. pylori infection was po...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Interna Publishing
2017-02-01
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| Series: | Acta Medica Indonesiana |
| Subjects: | |
| Online Access: | http://www.actamedindones.org/index.php/ijim/article/view/264 |
| _version_ | 1818179006383521792 |
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| author | Yudith Annisa Ayu Rezkitha Muhammad Miftahussurur Iswan A Nusi Ummi Maimunah Pangestu Adi Yoshio Yamaoka |
| author_facet | Yudith Annisa Ayu Rezkitha Muhammad Miftahussurur Iswan A Nusi Ummi Maimunah Pangestu Adi Yoshio Yamaoka |
| author_sort | Yudith Annisa Ayu Rezkitha |
| collection | DOAJ |
| description | We reported a male, 72 yo, Chinese ethnic with chief complaint black mushy defecation. Physical examination revealed pale on conjunctival palpebra which confirmed as anemia on complete blood count. Gastroduodenoscopy revealed a 3 mm ulcer at the antrum (Forrest stage III). H. pylori infection was positive based on five different test methods (urinary antibody tests, rapid urease test, culture, histology ad immunohistochemistry). Used polymerase chain reaction-based sequencing, we found the patient infected by CagA producing, East-Asian-type cagA and vacA s1m1-strain. Further analysis using 7 housekeeping genes confirmed that the strain categorized in to hspEAsia group. The patient was given continuous intravenous infusions of proton pump inhibitor and standard triple therapy regimens eradication of H. pylori. |
| first_indexed | 2024-12-11T20:57:00Z |
| format | Article |
| id | doaj.art-41988a2eb9e9447cbb1c3f2d0ce21e15 |
| institution | Directory Open Access Journal |
| issn | 0125-9326 2338-2732 |
| language | English |
| last_indexed | 2024-12-11T20:57:00Z |
| publishDate | 2017-02-01 |
| publisher | Interna Publishing |
| record_format | Article |
| series | Acta Medica Indonesiana |
| spelling | doaj.art-41988a2eb9e9447cbb1c3f2d0ce21e152022-12-22T00:51:04ZengInterna PublishingActa Medica Indonesiana0125-93262338-27322017-02-01484307313178An East-Asian-type cagA Helicobacter pylori Infected Patient with Clinical Manifestation Gastric UlcerYudith Annisa Ayu Rezkitha0Muhammad Miftahussurur1Iswan A Nusi2Ummi Maimunah3Pangestu Adi4Yoshio Yamaoka5Institute of Tropical Disease, Universitas Airlangga, Surabaya, IndonesiaDepartment of Environmental and Preventive Medicine, Oita University Faculty of Medicine, Yufu, JapanDepartment of Internal Medicine, Faculty of Medicine Universitas Airlangga - dr. Soetomo Teaching Hospital, Surabaya, IndonesiaDepartment of Internal Medicine, Faculty of Medicine Universitas Airlangga - dr. Soetomo Teaching Hospital, Surabaya, IndonesiaInstitute of Tropical Disease, Universitas Airlangga, Surabaya, Indonesia.Department of Environmental and Preventive Medicine, Oita University Faculty of Medicine, Yufu, JapanWe reported a male, 72 yo, Chinese ethnic with chief complaint black mushy defecation. Physical examination revealed pale on conjunctival palpebra which confirmed as anemia on complete blood count. Gastroduodenoscopy revealed a 3 mm ulcer at the antrum (Forrest stage III). H. pylori infection was positive based on five different test methods (urinary antibody tests, rapid urease test, culture, histology ad immunohistochemistry). Used polymerase chain reaction-based sequencing, we found the patient infected by CagA producing, East-Asian-type cagA and vacA s1m1-strain. Further analysis using 7 housekeeping genes confirmed that the strain categorized in to hspEAsia group. The patient was given continuous intravenous infusions of proton pump inhibitor and standard triple therapy regimens eradication of H. pylori.http://www.actamedindones.org/index.php/ijim/article/view/264Helicobacter pyloriGastric ulcerEast-Asian-type cagAvacA |
| spellingShingle | Yudith Annisa Ayu Rezkitha Muhammad Miftahussurur Iswan A Nusi Ummi Maimunah Pangestu Adi Yoshio Yamaoka An East-Asian-type cagA Helicobacter pylori Infected Patient with Clinical Manifestation Gastric Ulcer Acta Medica Indonesiana Helicobacter pylori Gastric ulcer East-Asian-type cagA vacA |
| title | An East-Asian-type cagA Helicobacter pylori Infected Patient with Clinical Manifestation Gastric Ulcer |
| title_full | An East-Asian-type cagA Helicobacter pylori Infected Patient with Clinical Manifestation Gastric Ulcer |
| title_fullStr | An East-Asian-type cagA Helicobacter pylori Infected Patient with Clinical Manifestation Gastric Ulcer |
| title_full_unstemmed | An East-Asian-type cagA Helicobacter pylori Infected Patient with Clinical Manifestation Gastric Ulcer |
| title_short | An East-Asian-type cagA Helicobacter pylori Infected Patient with Clinical Manifestation Gastric Ulcer |
| title_sort | east asian type caga helicobacter pylori infected patient with clinical manifestation gastric ulcer |
| topic | Helicobacter pylori Gastric ulcer East-Asian-type cagA vacA |
| url | http://www.actamedindones.org/index.php/ijim/article/view/264 |
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