Inhibition of MicroRNA‐155 Supports Endothelial Tight Junction Integrity Following Oxygen‐Glucose Deprivation

Inhibition of MicroRNA‐155 Supports Endothelial Tight Junction Integrity Following Oxygen‐Glucose Deprivation

Background Brain microvascular endothelial cells form a highly selective blood brain barrier regulated by the endothelial tight junctions. Cerebral ischemia selectively targets tight junction protein complexes, which leads to significant damage to cerebral microvasculature. Short noncoding molecules...

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Bibliographic Details
Main Authors: Juan Carlos Pena‐Philippides, Amy Sabrina Gardiner, Ernesto Caballero‐Garrido, Rong Pan, Yiliang Zhu, Tamara Roitbak
Format: Article
Language:English
Published: Wiley 2018-07-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
brain microvascular endothelial cells
endothelial barrier
microRNA
oxygen‐glucose deprivation
tight junctions
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.118.009244

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