Matrine and icariin can inhibit bovine viral diarrhoea virus replication by promoting type I interferon response in vitro

Bovine viral diarrhoea virus (BVDV) can cause diarrhoea (BVD) in an animal herd, leading to heavy economic losses. There are limited drugs available for treating and controlling BVD. This research aims to investigate the antiviral and immunoregulatory effects of two traditional Chinese herb extracts...

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Main Authors: Cai Dongjie, Shen Zifan, Tian Bin, Chen Jie, Zhang Yilin, Shen Liuhong, Wang Ya, Ma Xiaoping, Zuo Zhicai
Format: Article
Language:English
Published: Sciendo 2024-03-01
Series:Journal of Veterinary Research
Subjects:
Online Access:https://doi.org/10.2478/jvetres-2024-0013
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author Cai Dongjie
Shen Zifan
Tian Bin
Chen Jie
Zhang Yilin
Shen Liuhong
Wang Ya
Ma Xiaoping
Zuo Zhicai
author_facet Cai Dongjie
Shen Zifan
Tian Bin
Chen Jie
Zhang Yilin
Shen Liuhong
Wang Ya
Ma Xiaoping
Zuo Zhicai
author_sort Cai Dongjie
collection DOAJ
description Bovine viral diarrhoea virus (BVDV) can cause diarrhoea (BVD) in an animal herd, leading to heavy economic losses. There are limited drugs available for treating and controlling BVD. This research aims to investigate the antiviral and immunoregulatory effects of two traditional Chinese herb extracts against BVDV infection. The extracts are matrine and icariin, which have been proved to have immunostimulant and antiviral effects.
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spelling doaj.art-4198ae3427e146b181f1ff6e566fe1e92024-03-25T07:30:32ZengSciendoJournal of Veterinary Research2450-86082024-03-01681354410.2478/jvetres-2024-0013Matrine and icariin can inhibit bovine viral diarrhoea virus replication by promoting type I interferon response in vitroCai Dongjie0Shen Zifan1Tian Bin2Chen Jie3Zhang Yilin4Shen Liuhong5Wang Ya6Ma Xiaoping7Zuo Zhicai81College of Veterinary Medicine, Sichuan Agricultural University, 611130Chengdu, China1College of Veterinary Medicine, Sichuan Agricultural University, 611130Chengdu, China1College of Veterinary Medicine, Sichuan Agricultural University, 611130Chengdu, China1College of Veterinary Medicine, Sichuan Agricultural University, 611130Chengdu, China1College of Veterinary Medicine, Sichuan Agricultural University, 611130Chengdu, China1College of Veterinary Medicine, Sichuan Agricultural University, 611130Chengdu, China1College of Veterinary Medicine, Sichuan Agricultural University, 611130Chengdu, China1College of Veterinary Medicine, Sichuan Agricultural University, 611130Chengdu, China1College of Veterinary Medicine, Sichuan Agricultural University, 611130Chengdu, ChinaBovine viral diarrhoea virus (BVDV) can cause diarrhoea (BVD) in an animal herd, leading to heavy economic losses. There are limited drugs available for treating and controlling BVD. This research aims to investigate the antiviral and immunoregulatory effects of two traditional Chinese herb extracts against BVDV infection. The extracts are matrine and icariin, which have been proved to have immunostimulant and antiviral effects.https://doi.org/10.2478/jvetres-2024-0013bovine viral diarrhoea virusmatrineicariinantiviral effectimmunoregulation
spellingShingle Cai Dongjie
Shen Zifan
Tian Bin
Chen Jie
Zhang Yilin
Shen Liuhong
Wang Ya
Ma Xiaoping
Zuo Zhicai
Matrine and icariin can inhibit bovine viral diarrhoea virus replication by promoting type I interferon response in vitro
Journal of Veterinary Research
bovine viral diarrhoea virus
matrine
icariin
antiviral effect
immunoregulation
title Matrine and icariin can inhibit bovine viral diarrhoea virus replication by promoting type I interferon response in vitro
title_full Matrine and icariin can inhibit bovine viral diarrhoea virus replication by promoting type I interferon response in vitro
title_fullStr Matrine and icariin can inhibit bovine viral diarrhoea virus replication by promoting type I interferon response in vitro
title_full_unstemmed Matrine and icariin can inhibit bovine viral diarrhoea virus replication by promoting type I interferon response in vitro
title_short Matrine and icariin can inhibit bovine viral diarrhoea virus replication by promoting type I interferon response in vitro
title_sort matrine and icariin can inhibit bovine viral diarrhoea virus replication by promoting type i interferon response in vitro
topic bovine viral diarrhoea virus
matrine
icariin
antiviral effect
immunoregulation
url https://doi.org/10.2478/jvetres-2024-0013
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