Large overlap in neutrophil transcriptome between lupus and COVID-19 with limited lupus-specific gene expression

Objectives To illuminate the poorly understood aetiology of SLE by comparing the gene expression profile of SLE neutrophils with that of neutrophils from patients infected by SARS-CoV-2, a disease (COVID-19) with well-defined antigens and a similar type I interferon response.Methods RNA sequencing o...

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Bibliographic Details
Main Authors: Tomas Mustelin, Alison Bays, Rayan Najjar, Noga Rogel, Jose Mario Bello Pineda, Xiaoxing Wang, Megan Tran
Format: Article
Language:English
Published: BMJ Publishing Group 2024-01-01
Series:Lupus Science and Medicine
Online Access:https://lupus.bmj.com/content/11/1/e001059.full