Identifying Priorities for Harmonizing Guidelines for the Long-Term Surveillance of Childhood Cancer Survivors in the Chinese Children Cancer Group (CCCG)
PURPOSESurvivors of childhood cancer often experience treatment-related chronic health conditions. Given its vast population, China shares a large proportion of the global childhood cancer burden. Yet, screening and treatment of late effects in survivors of childhood cancer remain underaddressed in...
| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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American Society of Clinical Oncology
2021-12-01
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| Series: | JCO Global Oncology |
| Online Access: | https://ascopubs.org/doi/10.1200/GO.20.00534 |
| _version_ | 1818775277125238784 |
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| author | Yin Ting Cheung Hui Zhang Jiaoyang Cai Lung Wai Phillip Au-Doung Lok Sum Yang Cuixia Yan Fen Zhou Xiaojuan Chen Xianmin Guan Ching-Hon Pui Melissa M. Hudson Chi-kong Li |
| author_facet | Yin Ting Cheung Hui Zhang Jiaoyang Cai Lung Wai Phillip Au-Doung Lok Sum Yang Cuixia Yan Fen Zhou Xiaojuan Chen Xianmin Guan Ching-Hon Pui Melissa M. Hudson Chi-kong Li |
| author_sort | Yin Ting Cheung |
| collection | DOAJ |
| description | PURPOSESurvivors of childhood cancer often experience treatment-related chronic health conditions. Given its vast population, China shares a large proportion of the global childhood cancer burden. Yet, screening and treatment of late effects in survivors of childhood cancer remain underaddressed in most regions of China. This study aimed to identify high-priority late effects for harmonizing screening guidelines within the Chinese Children's Cancer Group (CCCG), as well as barriers and enablers of the implementation of surveillance recommendations in local practice.METHODSTo establish clinical consensus, 12 expert panelists who represent major institutions within the CCCG completed a Delphi survey and participated in a focus group discussion. The survey solicited ratings of the prevalence, severity, and priority for screening of 45 late effects. Major themes identified from the focus group were analyzed using thematic analysis.RESULTSThe Delphi survey identified eight high-priority late effects for harmonization within CCCG: osteonecrosis, osteoporosis, left ventricular dysfunction, secondary brain tumors, treatment-related myeloid leukemia, gonadal dysfunction, growth hormone deficiency, and neurocognitive deficits. The common barriers to implementing survivorship programs include lack of support and resources for clinicians to provide follow-up care. Patients were also concerned about privacy issues and lacked awareness of late effects. Many institutions also lacked rehabilitation expertise and referral pathways.CONCLUSIONBy identifying obstacles related to the professional setting, patient behavior, and organization of care, our study identified resources and a framework for establishing collaborative strategies to facilitate follow-up care of childhood cancer survivors in China. |
| first_indexed | 2024-12-18T10:54:29Z |
| format | Article |
| id | doaj.art-419cda0e17924554ae4d418f451dca4f |
| institution | Directory Open Access Journal |
| issn | 2687-8941 |
| language | English |
| last_indexed | 2024-12-18T10:54:29Z |
| publishDate | 2021-12-01 |
| publisher | American Society of Clinical Oncology |
| record_format | Article |
| series | JCO Global Oncology |
| spelling | doaj.art-419cda0e17924554ae4d418f451dca4f2022-12-21T21:10:23ZengAmerican Society of Clinical OncologyJCO Global Oncology2687-89412021-12-01726127610.1200/GO.20.00534Identifying Priorities for Harmonizing Guidelines for the Long-Term Surveillance of Childhood Cancer Survivors in the Chinese Children Cancer Group (CCCG)Yin Ting Cheung0Hui Zhang1Jiaoyang Cai2Lung Wai Phillip Au-Doung3Lok Sum Yang4Cuixia Yan5Fen Zhou6Xiaojuan Chen7Xianmin Guan8Ching-Hon Pui9Melissa M. Hudson10Chi-kong Li11School of Pharmacy, Faculty of Medicine, The Chinese University of Hong Kong, Hong KongDepartment of Hematology and Oncology, Guangzhou Women and Children's Medical Center, Guangzhou, ChinaKey Laboratory of Pediatric Hematology and Oncology Ministry of Health, Department of Hematology and Oncology, Pediatric Translational Medicine Institute, Shanghai Children's Medical Center, School of Medicine, Shanghai Jiao Tong University, Shanghai, ChinaSchool of Pharmacy, Faculty of Medicine, The Chinese University of Hong Kong, Hong KongSchool of Pharmacy, Faculty of Medicine, The Chinese University of Hong Kong, Hong KongDepartment of Hematology and Oncology, Guangzhou Women and Children's Medical Center, Guangzhou, ChinaPediatric Department, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, ChinaState Key Laboratory of Experimental Hematology, Department of Paediatrics Haematology, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, ChinaDivision of Hematology, Children's Hospital, Chongqing Medical University, Chongqing, ChinaDepartment of Oncology, St Jude Children's Research Hospital, Memphis, TNDepartment of Oncology, St Jude Children's Research Hospital, Memphis, TNDepartment of Paediatrics, Faculty of Medicine, The Chinese University of Hong Kong, Hong KongPURPOSESurvivors of childhood cancer often experience treatment-related chronic health conditions. Given its vast population, China shares a large proportion of the global childhood cancer burden. Yet, screening and treatment of late effects in survivors of childhood cancer remain underaddressed in most regions of China. This study aimed to identify high-priority late effects for harmonizing screening guidelines within the Chinese Children's Cancer Group (CCCG), as well as barriers and enablers of the implementation of surveillance recommendations in local practice.METHODSTo establish clinical consensus, 12 expert panelists who represent major institutions within the CCCG completed a Delphi survey and participated in a focus group discussion. The survey solicited ratings of the prevalence, severity, and priority for screening of 45 late effects. Major themes identified from the focus group were analyzed using thematic analysis.RESULTSThe Delphi survey identified eight high-priority late effects for harmonization within CCCG: osteonecrosis, osteoporosis, left ventricular dysfunction, secondary brain tumors, treatment-related myeloid leukemia, gonadal dysfunction, growth hormone deficiency, and neurocognitive deficits. The common barriers to implementing survivorship programs include lack of support and resources for clinicians to provide follow-up care. Patients were also concerned about privacy issues and lacked awareness of late effects. Many institutions also lacked rehabilitation expertise and referral pathways.CONCLUSIONBy identifying obstacles related to the professional setting, patient behavior, and organization of care, our study identified resources and a framework for establishing collaborative strategies to facilitate follow-up care of childhood cancer survivors in China.https://ascopubs.org/doi/10.1200/GO.20.00534 |
| spellingShingle | Yin Ting Cheung Hui Zhang Jiaoyang Cai Lung Wai Phillip Au-Doung Lok Sum Yang Cuixia Yan Fen Zhou Xiaojuan Chen Xianmin Guan Ching-Hon Pui Melissa M. Hudson Chi-kong Li Identifying Priorities for Harmonizing Guidelines for the Long-Term Surveillance of Childhood Cancer Survivors in the Chinese Children Cancer Group (CCCG) JCO Global Oncology |
| title | Identifying Priorities for Harmonizing Guidelines for the Long-Term Surveillance of Childhood Cancer Survivors in the Chinese Children Cancer Group (CCCG) |
| title_full | Identifying Priorities for Harmonizing Guidelines for the Long-Term Surveillance of Childhood Cancer Survivors in the Chinese Children Cancer Group (CCCG) |
| title_fullStr | Identifying Priorities for Harmonizing Guidelines for the Long-Term Surveillance of Childhood Cancer Survivors in the Chinese Children Cancer Group (CCCG) |
| title_full_unstemmed | Identifying Priorities for Harmonizing Guidelines for the Long-Term Surveillance of Childhood Cancer Survivors in the Chinese Children Cancer Group (CCCG) |
| title_short | Identifying Priorities for Harmonizing Guidelines for the Long-Term Surveillance of Childhood Cancer Survivors in the Chinese Children Cancer Group (CCCG) |
| title_sort | identifying priorities for harmonizing guidelines for the long term surveillance of childhood cancer survivors in the chinese children cancer group cccg |
| url | https://ascopubs.org/doi/10.1200/GO.20.00534 |
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