iPRESTO: Automated discovery of biosynthetic sub-clusters linked to specific natural product substructures.
Microbial specialised metabolism is full of valuable natural products that are applied clinically, agriculturally, and industrially. The genes that encode their biosynthesis are often physically clustered on the genome in biosynthetic gene clusters (BGCs). Many BGCs consist of multiple groups of co-...
Main Authors: | Joris J R Louwen, Satria A Kautsar, Sven van der Burg, Marnix H Medema, Justin J J van der Hooft |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2023-02-01
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Series: | PLoS Computational Biology |
Online Access: | https://doi.org/10.1371/journal.pcbi.1010462 |
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