The Importance of Non-neuronal Cell Types in hiPSC-Based Disease Modeling and Drug Screening

The Importance of Non-neuronal Cell Types in hiPSC-Based Disease Modeling and Drug Screening

Current applications of human induced pluripotent stem cell (hiPSC) technologies in patient-specific models of neurodegenerative and neuropsychiatric disorders tend to focus on neuronal phenotypes. Here, we review recent efforts toward advancing hiPSCs toward non-neuronal cell types of the central n...

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Bibliographic Details
Main Authors: David M. Gonzalez, Jill Gregory, Kristen J. Brennand
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-12-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
human induced pluripotent stem cells
drug screening
glia
schizophrenia
ALS
Rett syndrome
Online Access:http://journal.frontiersin.org/article/10.3389/fcell.2017.00117/full

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