Iron Oxide Nanocrystals for Magnetic Hyperthermia Applications
Magnetic nanocrystals have been investigated extensively in the past several years for several potential applications, such as information technology, MRI contrast agents, and for drug conjugation and delivery. A specific property of interest in biomedicine is magnetic hyperthermia—an increase in te...
| Main Authors: | , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2012-05-01
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| Series: | Nanomaterials |
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| Online Access: | http://www.mdpi.com/2079-4991/2/2/134 |
| _version_ | 1818173444849664000 |
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| author | Dale L. Huber Todd C. Monson Gennady A. Smolyakov Natalie L. Adolphi Nathan J. Withers Nathaniel C. Cook Antonio C. Rivera Salomon Maestas Surabhi Yadav Dimple Mathew Yekaterina I. Brandt Leisha M. Armijo Hugh D. C. Smyth Marek Osiński |
| author_facet | Dale L. Huber Todd C. Monson Gennady A. Smolyakov Natalie L. Adolphi Nathan J. Withers Nathaniel C. Cook Antonio C. Rivera Salomon Maestas Surabhi Yadav Dimple Mathew Yekaterina I. Brandt Leisha M. Armijo Hugh D. C. Smyth Marek Osiński |
| author_sort | Dale L. Huber |
| collection | DOAJ |
| description | Magnetic nanocrystals have been investigated extensively in the past several years for several potential applications, such as information technology, MRI contrast agents, and for drug conjugation and delivery. A specific property of interest in biomedicine is magnetic hyperthermia—an increase in temperature resulting from the thermal energy released by magnetic nanocrystals in an external alternating magnetic field. Iron oxide nanocrystals of various sizes and morphologies were synthesized and tested for specific losses (heating power) using frequencies of 111.1 kHz and 629.2 kHz, and corresponding magnetic field strengths of 9 and 25 mT. Polymorphous nanocrystals as well as spherical nanocrystals and nanowires in paramagnetic to ferromagnetic size range exhibited good heating power. A remarkable 30 °C temperature increase was observed in a nanowire sample at 111 kHz and magnetic field of 25 mT (19.6 kA/m), which is very close to the typical values of 100 kHz and 20 mT used in medical treatments. |
| first_indexed | 2024-12-11T19:28:37Z |
| format | Article |
| id | doaj.art-41a61b537f3b4a24a4bc20fbb4117a84 |
| institution | Directory Open Access Journal |
| issn | 2079-4991 |
| language | English |
| last_indexed | 2024-12-11T19:28:37Z |
| publishDate | 2012-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Nanomaterials |
| spelling | doaj.art-41a61b537f3b4a24a4bc20fbb4117a842022-12-22T00:53:21ZengMDPI AGNanomaterials2079-49912012-05-012213414610.3390/nano2020134Iron Oxide Nanocrystals for Magnetic Hyperthermia ApplicationsDale L. HuberTodd C. MonsonGennady A. SmolyakovNatalie L. AdolphiNathan J. WithersNathaniel C. CookAntonio C. RiveraSalomon MaestasSurabhi YadavDimple MathewYekaterina I. BrandtLeisha M. ArmijoHugh D. C. SmythMarek OsińskiMagnetic nanocrystals have been investigated extensively in the past several years for several potential applications, such as information technology, MRI contrast agents, and for drug conjugation and delivery. A specific property of interest in biomedicine is magnetic hyperthermia—an increase in temperature resulting from the thermal energy released by magnetic nanocrystals in an external alternating magnetic field. Iron oxide nanocrystals of various sizes and morphologies were synthesized and tested for specific losses (heating power) using frequencies of 111.1 kHz and 629.2 kHz, and corresponding magnetic field strengths of 9 and 25 mT. Polymorphous nanocrystals as well as spherical nanocrystals and nanowires in paramagnetic to ferromagnetic size range exhibited good heating power. A remarkable 30 °C temperature increase was observed in a nanowire sample at 111 kHz and magnetic field of 25 mT (19.6 kA/m), which is very close to the typical values of 100 kHz and 20 mT used in medical treatments.http://www.mdpi.com/2079-4991/2/2/134iron oxide nanocrystalshyperthermiathermotherapyferrofluid |
| spellingShingle | Dale L. Huber Todd C. Monson Gennady A. Smolyakov Natalie L. Adolphi Nathan J. Withers Nathaniel C. Cook Antonio C. Rivera Salomon Maestas Surabhi Yadav Dimple Mathew Yekaterina I. Brandt Leisha M. Armijo Hugh D. C. Smyth Marek Osiński Iron Oxide Nanocrystals for Magnetic Hyperthermia Applications Nanomaterials iron oxide nanocrystals hyperthermia thermotherapy ferrofluid |
| title | Iron Oxide Nanocrystals for Magnetic Hyperthermia Applications |
| title_full | Iron Oxide Nanocrystals for Magnetic Hyperthermia Applications |
| title_fullStr | Iron Oxide Nanocrystals for Magnetic Hyperthermia Applications |
| title_full_unstemmed | Iron Oxide Nanocrystals for Magnetic Hyperthermia Applications |
| title_short | Iron Oxide Nanocrystals for Magnetic Hyperthermia Applications |
| title_sort | iron oxide nanocrystals for magnetic hyperthermia applications |
| topic | iron oxide nanocrystals hyperthermia thermotherapy ferrofluid |
| url | http://www.mdpi.com/2079-4991/2/2/134 |
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