Simultaneous determination of mometasone furoate and calcipotriol in a binary mixture by validated HPLC and chemometric-assisted UV spectrophotometric methods and identification of degradation products by LC-MS

Simultaneous determination of mometasone furoate and calcipotriol in a binary mixture by validated HPLC and chemometric-assisted UV spectrophotometric methods and identification of degradation products by LC-MS

Objective(s): A new binary mixture containing mometasone furoate (MF) and calcipotriol (CP) is suggested to manage psoriasis; since the combined stability profile of these drugs is poorly understood.Materials and Methods: Herein MF, CP, and their mixtures were subjected to various stress conditions....

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Bibliographic Details
Main Authors: Maryam Jahani, Maryam Akaberi, Tahereh Heidari, Hossein Kamali, Mozhgan Nejabat, Omid Rajabi, Farzin Hadizadeh
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2023-01-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
calcipotriol
hplc
mometasone furoate
spectrophotometric
stress study
validation
Online Access:https://ijbms.mums.ac.ir/article_21306_a5eeec787f1efb39bcbad8be07ad1b13.pdf

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