Intestinal probiotics E. coli Nissle 1917 as a targeted vehicle for delivery of p53 and Tum-5 to solid tumors for cancer therapy

Intestinal probiotics E. coli Nissle 1917 as a targeted vehicle for delivery of p53 and Tum-5 to solid tumors for cancer therapy

Abstract Traditional cancer therapies, such as surgery treatment, radiotherapy, and chemotherapy, often fail to completely eliminate tumor cells in an anaerobic microenvironment of tumor regions. In contrast to these traditional cancer therapies, the use of targeted delivery vectors to deliver antic...

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Bibliographic Details
Main Authors: Lian He, Huijun Yang, Jianli Tang, Zhudong Liu, Yiyan Chen, Binghua Lu, Haocheng He, Sijia Tang, Yunjun Sun, Fei Liu, Xuezhi Ding, Youming Zhang, Shengbiao Hu, Liqiu Xia
Format: Article
Language:English
Published: BMC 2019-06-01
Series:Journal of Biological Engineering
Subjects:
E.coli Nissle 1917
Targeted cancer therapy
p53
Tum-5
Gene therapy
Online Access:http://link.springer.com/article/10.1186/s13036-019-0189-9

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