Pharmacometric Evaluation of Umbilical Cord Blood Concentration-Based Early Initiation of Treatment in Methadone-Exposed Preterm Neonates

Pharmacometric Evaluation of Umbilical Cord Blood Concentration-Based Early Initiation of Treatment in Methadone-Exposed Preterm Neonates

In methadone-exposed preterm neonates, early identification of those at risk of severe neonatal abstinence syndrome (NAS) and use of a methadone dosing regimen that can provide effective and safe drug exposure are two important aspects of optimal care. To this end, we reviewed 17 methadone dosing re...

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Bibliographic Details
Main Authors: Samira Samiee-Zafarghandy, Tamara van Donge, Karel Allegaert, John van den Anker
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Children
Subjects:
preterm neonate
methadone
neonatal abstinence syndrome
dosing
Online Access:https://www.mdpi.com/2227-9067/8/3/174

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