Liquid Chromatography–Tandem Mass Spectrometry in Newborn Screening Laboratories

Liquid Chromatography–Tandem Mass Spectrometry in Newborn Screening Laboratories

Tandem mass spectrometry (MS/MS) is the most universal platform currently available for the analysis of enzymatic activities and biomarkers in dried blood spots (DBS) for applications in newborn screening (NBS). Among the MS/MS applications in NBS, the most common is flow-injection analysis (FIA-) M...

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Bibliographic Details
Main Authors: Michael H. Gelb, Khaja Basheeruddin, Alberto Burlina, Hsiao-Jan Chen, Yin-Hsiu Chien, George Dizikes, Christine Dorley, Roberto Giugliani, Amy Hietala, Xinying Hong, Shu-Min Kao, Hamid Khaledi, Tracy Klug, Francyne Kubaski, Hsuan-Chieh Liao, Monica Martin, Adrienne Manning, Joseph Orsini, Yin Peng, Enzo Ranieri, Andreas Rohrwasser, Nicolas Szabo-Fresnais, Coleman T. Turgeon, Frédérick M. Vaz, Li-yun Wang, Dietrich Matern
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:International Journal of Neonatal Screening
Subjects:
newborn screening
tandem mass spectrometry
liquid chromatography
dried blood spots
inborn errors of metabolism
reflex testing
Online Access:https://www.mdpi.com/2409-515X/8/4/62

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