Plasma Antioxidant Vitamins Levels and Lipid Peroxidation in Breast Cancer Patients

Oxidative stress arises when there is an imbalance between reactive oxygen species (ROSs) and scavenging capacity of antioxidants, and it can induce and progress many diseases such as breast cancer. The present study was conducted to investigate the status of plasma antioxidative vitamins (E and C)...

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Main Authors: T Aghvami, M Djalali, A Keshavarz, MR Sadeghi, H Zeraati, H Sadrzadeh Yeganeh, M Negahdar
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2006-03-01
Series:Iranian Journal of Public Health
Subjects:
Online Access:https://ijph.tums.ac.ir/index.php/ijph/article/view/2189
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author T Aghvami
M Djalali
A Keshavarz
MR Sadeghi
H Zeraati
H Sadrzadeh Yeganeh
M Negahdar
author_facet T Aghvami
M Djalali
A Keshavarz
MR Sadeghi
H Zeraati
H Sadrzadeh Yeganeh
M Negahdar
author_sort T Aghvami
collection DOAJ
description Oxidative stress arises when there is an imbalance between reactive oxygen species (ROSs) and scavenging capacity of antioxidants, and it can induce and progress many diseases such as breast cancer. The present study was conducted to investigate the status of plasma antioxidative vitamins (E and C) and lipid peroxidation on 50 untreated breast cancer patients and 50 healthy age-matched women. The results revealed that plasma vitamin E and vitamin E adjusted for the sum of cholesterol and triglycerides decreased significantly in patients group (P< 0.05). We could also observe that vitamin E adjusted for lipid was significantly different in various stages of breast cancer. On the other hand, the level of malondialdehyde increased significantly in patients as compared to the controls (P
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spelling doaj.art-41b079fcd49b400aa1556f4cb88c84bc2022-12-21T17:44:32ZengTehran University of Medical SciencesIranian Journal of Public Health2251-60852251-60932006-03-01351Plasma Antioxidant Vitamins Levels and Lipid Peroxidation in Breast Cancer Patients T Aghvami0 M Djalali1 A Keshavarz2 MR Sadeghi3 H Zeraati4 H Sadrzadeh Yeganeh5 M Negahdar6 Oxidative stress arises when there is an imbalance between reactive oxygen species (ROSs) and scavenging capacity of antioxidants, and it can induce and progress many diseases such as breast cancer. The present study was conducted to investigate the status of plasma antioxidative vitamins (E and C) and lipid peroxidation on 50 untreated breast cancer patients and 50 healthy age-matched women. The results revealed that plasma vitamin E and vitamin E adjusted for the sum of cholesterol and triglycerides decreased significantly in patients group (P< 0.05). We could also observe that vitamin E adjusted for lipid was significantly different in various stages of breast cancer. On the other hand, the level of malondialdehyde increased significantly in patients as compared to the controls (Phttps://ijph.tums.ac.ir/index.php/ijph/article/view/2189Malondialdehyde
spellingShingle T Aghvami
M Djalali
A Keshavarz
MR Sadeghi
H Zeraati
H Sadrzadeh Yeganeh
M Negahdar
Plasma Antioxidant Vitamins Levels and Lipid Peroxidation in Breast Cancer Patients
Iranian Journal of Public Health
Malondialdehyde
title Plasma Antioxidant Vitamins Levels and Lipid Peroxidation in Breast Cancer Patients
title_full Plasma Antioxidant Vitamins Levels and Lipid Peroxidation in Breast Cancer Patients
title_fullStr Plasma Antioxidant Vitamins Levels and Lipid Peroxidation in Breast Cancer Patients
title_full_unstemmed Plasma Antioxidant Vitamins Levels and Lipid Peroxidation in Breast Cancer Patients
title_short Plasma Antioxidant Vitamins Levels and Lipid Peroxidation in Breast Cancer Patients
title_sort plasma antioxidant vitamins levels and lipid peroxidation in breast cancer patients
topic Malondialdehyde
url https://ijph.tums.ac.ir/index.php/ijph/article/view/2189
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