Phase II Study of a Bi-Weekly Chemotherapy Regimen of Combined Liposomal Paclitaxel and Nedaplatin for the Treatment of Advanced Squamous Cell Lung Cancer

Phase II Study of a Bi-Weekly Chemotherapy Regimen of Combined Liposomal Paclitaxel and Nedaplatin for the Treatment of Advanced Squamous Cell Lung Cancer

The platinum-based, two-drug, 3-week regimen is currently the main first-line chemotherapy program for the treatment of advanced squamous cell lung cancer. The aim of this phase II clinical study was to evaluate the efficacy and adverse events of the bi-weekly program of liposomal paclitaxel combine...

Full description

Bibliographic Details
Main Authors:	Wei-Ze Lv, Zhong Lin, Si-Yang Wang, Bao-Jun Lv, Zhi-Hui Wang, Mei Xiao, Xiao-Lu Xu, Pei-Jian Peng
Format:	Article
Language:	English
Published:	Elsevier 2019-04-01
Series:	Translational Oncology
Online Access:	http://www.sciencedirect.com/science/article/pii/S1936523318306168

Similar Items

Multi-institutional prospective study of nedaplatin plus S-1 chemotherapy in recurrent and metastatic nasopharyngeal carcinoma patients after failure of platinum-containing regimens
by: Pei-Jian Peng, et al.
Published: (2017-02-01)

Efficacy and safety of nanoparticle albumin-bound paclitaxel plus cisplatin or nedaplatin plus tegafur/gimeracil/oteracil as induction chemotherapy regimen for hypopharyngeal cancer
by: Cailing Jiang, et al.
Published: (2025-02-01)

Thyroid collision tumour with pulmonary metastases treated effectively with nedaplatin and paclitaxel chemotherapy: A case report
by: Feng Liu, et al.
Published: (2023-11-01)

Nedaplatin: a cisplatin derivative in cancer chemotherapy
by: Shimada M, et al.
Published: (2013-05-01)

Efficacy and Safety of the PD-1 Inhibitor Combined with Albumin-Bound Paclitaxel and Nedaplatin in Preoperative Neoadjuvant Therapy of Unresectable Stage III Lung Squamous Cell Carcinoma
by: Xu H, et al.
Published: (2022-12-01)

The efficiency of liposomal paclitaxel versus docetaxel in neoadjuvant chemotherapy with the TPF regimen for locally advanced nasopharyngeal carcinoma: a retrospective study
by: Zhi Yang, et al.
Published: (2024-10-01)

Efficacy and safety of pemetrexed and nedaplatin followed by pemetrexed maintenance therapy in advanced lung adenocarcinoma
by: Lin Z, et al.
Published: (2017-11-01)

Neoadjuvant chemotherapy with liposomal paclitaxel plus platinum for locally advanced esophageal squamous cell cancer: Results from a retrospective study
by: Wenzhong Wang, et al.
Published: (2022-03-01)

Chemotherapy in Metastatic NSCLC – New Regimens (Pemetrexed, nab-Paclitaxel)
by: Vera eHirsh, et al.
Published: (2014-07-01)

Evaluation of the efficacy and feasibility of concurrent weekly docetaxel-nedaplatin and hypo-fractionated radiotherapy in atypical histologic subtypes of primary and metastatic mediastinal malignancies
by: FanJun Meng, et al.
Published: (2022-10-01)

Docetaxel Plus Nedaplatin or Carboplatin as Second-Line Chemotherapy for Advanced Lung Squamous Cell Carcinoma in Real-World Practice: A Single-Center Experience
by: Jian Zhong MD, et al.
Published: (2023-11-01)

Phase II trial of docetaxel combined with nedaplatin for patients with recurrent and metastatic nasopharyngeal carcinoma
by: Peng PJ, et al.
Published: (2015-12-01)

Dose-dense chemotherapy with weekly paclitaxel and 3-weekly carboplatin for recurrent ovarian cancer
by: Wei-Chun Chen, et al.
Published: (2020-01-01)

Induction chemotherapy with cisplatin plus weekly paclitaxel followed by chemoradiotherapy for locally advanced squamous cell carcinoma of the head and neck
by: Sargeele Silva, et al.
Published: (2019-01-01)

Clinical Efficacy of Liposomal Paclitaxel in Maintenance Treatment of Patients with Advanced Squamous Cell Lung Carcinoma
by: SHAO Jianghe, et al.
Published: (2018-08-01)

Nedaplatin use in patients with hypersensitivity reaction episodes to carboplatin
by: Kenro Chikazawa, et al.
Published: (2020-07-01)

Phase II study of nedaplatin and amrubicin as first‐line treatment for advanced squamous cell lung cancer
by: Hirokazu Taniguchi, et al.
Published: (2019-09-01)

Erratum on: Chemotherapy in metastatic NSCLC – new regimens (pemetrexed, nab-paclitaxel)
by: Frontiers in Oncology Editorial Office
Published: (2014-10-01)

Weekly paclitaxel as metronomic palliative chemotherapy in small cell lung cancer
by: Vanita Noronha, et al.
Published: (2016-01-01)

Case Report: Etoposide-nedaplatin induced rhabdomyolysis in a small cell lung cancer patient
by: Xiaohu Xu, et al.
Published: (2023-08-01)

Tolerance of weekly metronomic paclitaxel and carboplatin as neoadjuvant chemotherapy in advanced ovarian cancer patients who are unlikely to tolerate 3 weekly paclitaxel and carboplatin
by: S B Dessai, et al.
Published: (2016-01-01)

A Radomized Clinical Trial on the Clinical Efficacy and Toxicities of Single-agent Paclitaxel Liposome versus Paclitaxel Liposome plus Oxaliplatin as First-line  Chemotherapy for Advanced Non-small Cell Lung Cancer in Elderly Patients
by: Xiaomei ZENG, et al.
Published: (2012-02-01)

Comparative clinical studies of primary chemoradiotherapy versus S-1 and nedaplatin chemotherapy against stage IVb oesophageal squamous cell carcinoma: a multicentre open-label randomised controlled trial
by: Xin Wang, et al.
Published: (2022-04-01)

Trajectories of squamous cell carcinoma antigen and outcomes of patients with advanced penile cancer after chemotherapy based on paclitaxel, ifosfamid, and cisplatin regimen
by: Nan Ma, et al.
Published: (2024-06-01)

Neoadjuvant chemotherapy with weekly cisplatin and paclitaxel followed by chemoradiation for locally advanced cervical cancer
by: Jing Li, et al.
Published: (2023-01-01)

Weekly chemotherapy with cisplatin and paclitaxel in advanced NSCLC: a phase II study
by: G. Buccheri, et al.
Published: (2016-02-01)

Encapsulation of Nedaplatin in Novel PEGylated Liposomes Increases Its Cytotoxicity and Genotoxicity against A549 and U2OS Human Cancer Cells
by: Salma El-Shafie, et al.
Published: (2020-09-01)

Hypomagnesemia because of nedaplatin for cervical cancer: A case report
by: Jun Komoda, et al.
Published: (2023-07-01)

Modified bi‐weekly cetuximab‐cisplatin and 5‐FU/leucovorin based regimen for effective treatment of recurrent/metastatic head and neck squamous cell carcinoma to reduce chemotherapy exposure of patients
by: Amichay Meirovitz, et al.
Published: (2022-03-01)

Replacement of cisplatin with nedaplatin in a definitive 5-fluorouracil/cisplatin-based chemoradiotherapy in Japanese patients with esophageal squamous cell carcinoma
by: Akiko Kuwahara, Motohiro Yamamori, Kohshi Nishiguchi, Tatsuya Okuno, Naoko Chayahara, Ikuya Miki, Takao Tamura, Tsubasa Inokuma, Yoshiji Takemoto, Tsutomu Nakamura, Kazusaburo Kataoka, Toshiyuki Sakaeda
Published: (2009-01-01)

Feasibility of definitive chemoradiation therapy with nedaplatin and 5-fluorouracil in elderly patients with esophageal squamous cell carcinoma: A retrospective study
by: Akinori Watanabe, MD, et al.
Published: (2018-07-01)

Nedaplatin-based chemotherapy or cisplatin-based chemotherapy combined with intensity-modulated radiotherapy achieve similar efficacy for stage II-IVa nasopharyngeal carcinoma patients
by: Chao Deng, et al.
Published: (2022-07-01)

Weekly vs Every-3-Week Carboplatin with Weekly Paclitaxel in Neoadjuvant Chemotherapy for Triple-Negative Breast Cancer: A Retrospective Analysis
by: Landry KK, et al.
Published: (2022-03-01)

Nedaplatin as a Single-Agent Chemotherapy May Support Palliative Therapy for Patients with Adenoid Cystic Carcinoma: A Case Report
by: Hiroyuki Hirakawa, et al.
Published: (2017-08-01)

Efficacy Comparison Between Weekly and Triweekly Regimens of Carboplatin-paclitaxel in Non-small Cell Lung Cancer
by: Serdar ATA, et al.
Published: (2023-09-01)

Liposomal paclitaxel versus docetaxel in induction chemotherapy using Taxanes, cisplatin and 5-fluorouracil for locally advanced nasopharyngeal carcinoma
by: Sai-Lan Liu, et al.
Published: (2018-12-01)

Efficacy and safety of paclitaxel liposome versus paclitaxel in combination with carboplatin in the first-line chemotherapy for ovarian cancer: a multicenter, open-label, non-inferiority, randomized controlled trial
by: Rong Li, et al.
Published: (2024-06-01)

Cilostazol protective effect on nedaplatin-induced genotoxicity in cultured human lymphocytes
by: Karem H. Alzoubi, et al.
Published: (2025-06-01)

Chemoradiotherapy with paclitaxel liposome plus cisplatin for locally advanced esophageal squamous cell carcinoma: A retrospective analysis
by: Qiong Yi, et al.
Published: (2023-03-01)

Induction chemotherapy with paclitaxel and cisplatin to concurrent radiotherapy and weekly paclitaxel in the treatment of loco-regionally advanced, stage IV (M0), head and neck squamous cell carcinoma. Mature results of a prospective study
by: Pergolizzi Stefano, et al.
Published: (2011-11-01)