Inflammasomes as therapeutic targets in human diseases
Abstract Inflammasomes are protein complexes of the innate immune system that initiate inflammation in response to either exogenous pathogens or endogenous danger signals. Inflammasome multiprotein complexes are composed of three parts: a sensor protein, an adaptor, and pro-caspase-1. Activation of...
Main Authors: | Yangxin Li, Hui Huang, Bin Liu, Yu Zhang, Xiangbin Pan, Xi-Yong Yu, Zhenya Shen, Yao-Hua Song |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2021-07-01
|
Series: | Signal Transduction and Targeted Therapy |
Online Access: | https://doi.org/10.1038/s41392-021-00650-z |
Similar Items
-
Ribosome biogenesis in disease: new players and therapeutic targets
by: Lijuan Jiao, et al.
Published: (2023-01-01) -
Stem cell-derived exosomes repair ischemic muscle injury by inhibiting the tumor suppressor Rb1-mediated NLRP3 inflammasome pathway
by: Yanli Wang, et al.
Published: (2021-03-01) -
The role of inflammasomes in human diseases and their potential as therapeutic targets
by: Jing Yao, et al.
Published: (2024-01-01) -
Inflammasome and Its Therapeutic Targeting in Rheumatoid Arthritis
by: Qi Jiang, et al.
Published: (2022-01-01) -
Therapeutic targeting of the inflammasome in myeloid malignancies
by: Samarpana Chakraborty, et al.
Published: (2021-09-01)