Benefits and risks of the subcutaneous immunotherapy with acari extracts in allergic rhinoconjunctivitis and bronchial asthma
The records of patients from the Allergology Service in the Previsora Policlinic, Camagüey were revised to evaluate benefits and risks of the subcutaneous immunotherapy (ITSC) with extracts of acari. The study was observational, analytic and retrospective of cases and controls in allergic rhinoco...
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| Format: | Article |
| Language: | English |
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Finlay Ediciones
2014-12-01
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| Series: | VacciMonitor |
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| Online Access: | http://scielo.sld.cu/scielo.php?script=sci_pdf&pid=S1025-028X2014000300007&lng=es&nrm=iso&tlng=es |
| _version_ | 1828823331744251904 |
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| author | Olimpio Rodríguez-Santos Rodolfo Celio-Murillo Alfredo Martin Laurrabaquio-Miranda |
| author_facet | Olimpio Rodríguez-Santos Rodolfo Celio-Murillo Alfredo Martin Laurrabaquio-Miranda |
| author_sort | Olimpio Rodríguez-Santos |
| collection | DOAJ |
| description | The records of patients from the Allergology Service in the Previsora Policlinic, Camagüey were
revised to evaluate benefits and risks of the subcutaneous immunotherapy (ITSC) with extracts
of acari. The study was observational, analytic and retrospective of cases and controls in allergic
rhinoconjunctivitis and bronchial asthma. A total of 160 subjects, older than 18 years old, were
chosen. Eighty out of them had already received ITSC with dose increase during 13 weeks and
maintenance with monthly injections during 18 months. A total of 80 patients who only received
prevention measures and medications during the crises were paired. Questionnaires were
applied for quality of rhinoconjunctivitis life and asthma, about the consumption of medications
and the frequency of the crises. The adverse events were measured, as they were local and
systemic to the cutaneous tests, to the ITSC and the different pharmacological treatments. There
was a significant increase of the punctuation of life quality questionnaires, (p=0.011). The
consumption of medications decreased in both the cases and the controls, without significant
differences (p=0.083). The frequency of the rhinitis and asthma crises decrease in the group of
ITSC (p=0.029). Slight local and systemic reactions were reported in both groups with Odds
ratio (OR)=2.029 in the ITSC group, with a 95% confidence interval of 1.114–3.967 (p=0.019).
The results show that the subcutaneous immunotherapy with acari offers benefits and few risks
to patients with allergic rhinoconjunctivitis and asthma. |
| first_indexed | 2024-12-12T13:34:11Z |
| format | Article |
| id | doaj.art-41b62a6c1f924e0ebd9e71f350c4b7e4 |
| institution | Directory Open Access Journal |
| issn | 1025-028X 1025-0298 |
| language | English |
| last_indexed | 2024-12-12T13:34:11Z |
| publishDate | 2014-12-01 |
| publisher | Finlay Ediciones |
| record_format | Article |
| series | VacciMonitor |
| spelling | doaj.art-41b62a6c1f924e0ebd9e71f350c4b7e42022-12-22T00:23:00ZengFinlay EdicionesVacciMonitor1025-028X1025-02982014-12-01233124132Benefits and risks of the subcutaneous immunotherapy with acari extracts in allergic rhinoconjunctivitis and bronchial asthmaOlimpio Rodríguez-Santos0Rodolfo Celio-Murillo1Alfredo Martin Laurrabaquio-Miranda2Servicio Alergia Policlínico Universitario Docente, Previsora Camagüey Cuba.Facultad de Medicina de la Benemérita Universidad Autónoma de Puebla (BUAP) Campus Tehuacán México.Servicio de Alergia e Inmunología Clínica Hospital Regional Lic. Adolfo López Mateos, México.The records of patients from the Allergology Service in the Previsora Policlinic, Camagüey were revised to evaluate benefits and risks of the subcutaneous immunotherapy (ITSC) with extracts of acari. The study was observational, analytic and retrospective of cases and controls in allergic rhinoconjunctivitis and bronchial asthma. A total of 160 subjects, older than 18 years old, were chosen. Eighty out of them had already received ITSC with dose increase during 13 weeks and maintenance with monthly injections during 18 months. A total of 80 patients who only received prevention measures and medications during the crises were paired. Questionnaires were applied for quality of rhinoconjunctivitis life and asthma, about the consumption of medications and the frequency of the crises. The adverse events were measured, as they were local and systemic to the cutaneous tests, to the ITSC and the different pharmacological treatments. There was a significant increase of the punctuation of life quality questionnaires, (p=0.011). The consumption of medications decreased in both the cases and the controls, without significant differences (p=0.083). The frequency of the rhinitis and asthma crises decrease in the group of ITSC (p=0.029). Slight local and systemic reactions were reported in both groups with Odds ratio (OR)=2.029 in the ITSC group, with a 95% confidence interval of 1.114–3.967 (p=0.019). The results show that the subcutaneous immunotherapy with acari offers benefits and few risks to patients with allergic rhinoconjunctivitis and asthma.http://scielo.sld.cu/scielo.php?script=sci_pdf&pid=S1025-028X2014000300007&lng=es&nrm=iso&tlng=esimmunotherapyacariasthmarhinoconjunctivitis |
| spellingShingle | Olimpio Rodríguez-Santos Rodolfo Celio-Murillo Alfredo Martin Laurrabaquio-Miranda Benefits and risks of the subcutaneous immunotherapy with acari extracts in allergic rhinoconjunctivitis and bronchial asthma VacciMonitor immunotherapy acari asthma rhinoconjunctivitis |
| title | Benefits and risks of the subcutaneous immunotherapy with acari extracts in allergic rhinoconjunctivitis and bronchial asthma |
| title_full | Benefits and risks of the subcutaneous immunotherapy with acari extracts in allergic rhinoconjunctivitis and bronchial asthma |
| title_fullStr | Benefits and risks of the subcutaneous immunotherapy with acari extracts in allergic rhinoconjunctivitis and bronchial asthma |
| title_full_unstemmed | Benefits and risks of the subcutaneous immunotherapy with acari extracts in allergic rhinoconjunctivitis and bronchial asthma |
| title_short | Benefits and risks of the subcutaneous immunotherapy with acari extracts in allergic rhinoconjunctivitis and bronchial asthma |
| title_sort | benefits and risks of the subcutaneous immunotherapy with acari extracts in allergic rhinoconjunctivitis and bronchial asthma |
| topic | immunotherapy acari asthma rhinoconjunctivitis |
| url | http://scielo.sld.cu/scielo.php?script=sci_pdf&pid=S1025-028X2014000300007&lng=es&nrm=iso&tlng=es |
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