Efficacy of Resection of Lateral Wall of Endolymphatic Sac for Treatment of Meniere's Disease
BackgroundTo explore the long-term efficacy and safety of resection of the lateral wall of the endolymphatic sac for the treatment of intractable Meniere's disease (MD) as an alternative surgical procedure for treating this disorder.MethodsData from 73 patients who were referred to our hospital...
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| Format: | Article |
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Frontiers Media S.A.
2022-03-01
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| Series: | Frontiers in Neurology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fneur.2022.827462/full |
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| author | Daogong Zhang Yafeng Lv Xiaofei Li Yongdong Song Ligang Kong Zhaomin Fan Haibo Wang |
| author_facet | Daogong Zhang Yafeng Lv Xiaofei Li Yongdong Song Ligang Kong Zhaomin Fan Haibo Wang |
| author_sort | Daogong Zhang |
| collection | DOAJ |
| description | BackgroundTo explore the long-term efficacy and safety of resection of the lateral wall of the endolymphatic sac for the treatment of intractable Meniere's disease (MD) as an alternative surgical procedure for treating this disorder.MethodsData from 73 patients who were referred to our hospital and diagnosed with unilateral MD between January 2015 and June 2019 were retrospectively analyzed in this study. Seventy-three patients who had frequent vertigo even after receiving standardized conservative treatment for at least half a year underwent resection of the lateral wall of the endolymphatic sac. Vertigo control and auditory function were assessed. Pure tone audiometry, caloric test, and vestibular evoked myogenic potential were performed to evaluate audiological and vestibular functions. The post-operative follow-up duration was more than 2 years.ResultsAmong the 73 patients (male 34 cases, female 39 cases; age 20–69 years, average 51.4), vertigo was controlled effectively for 66 cases (90.4%) after 2 years of follow-up; 45 cases (61.6%) were completely controlled, and 21 cases (28.8%) were substantially controlled in this study. The patients of 16.4% had hearing loss with more than 10 dB change based on the four-tone average (0.5, 1, 2 and 3 kHz). No patient had a facial nerve weakness, cerebrospinal fluid leakage, or other complications.ConclusionResection of the lateral wall of the endolymphatic sac, which can effectively control vertiginous symptoms in intractable MD patients, represents an effective and safe therapy for this disease. Resection of the lateral wall of the endolymphatic sac is expected to be used as an alternative treatment for MD. |
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| format | Article |
| id | doaj.art-41b686149a0b4f99bff4f775a62b47d7 |
| institution | Directory Open Access Journal |
| issn | 1664-2295 |
| language | English |
| last_indexed | 2024-12-13T08:33:27Z |
| publishDate | 2022-03-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Neurology |
| spelling | doaj.art-41b686149a0b4f99bff4f775a62b47d72022-12-21T23:53:42ZengFrontiers Media S.A.Frontiers in Neurology1664-22952022-03-011310.3389/fneur.2022.827462827462Efficacy of Resection of Lateral Wall of Endolymphatic Sac for Treatment of Meniere's DiseaseDaogong ZhangYafeng LvXiaofei LiYongdong SongLigang KongZhaomin FanHaibo WangBackgroundTo explore the long-term efficacy and safety of resection of the lateral wall of the endolymphatic sac for the treatment of intractable Meniere's disease (MD) as an alternative surgical procedure for treating this disorder.MethodsData from 73 patients who were referred to our hospital and diagnosed with unilateral MD between January 2015 and June 2019 were retrospectively analyzed in this study. Seventy-three patients who had frequent vertigo even after receiving standardized conservative treatment for at least half a year underwent resection of the lateral wall of the endolymphatic sac. Vertigo control and auditory function were assessed. Pure tone audiometry, caloric test, and vestibular evoked myogenic potential were performed to evaluate audiological and vestibular functions. The post-operative follow-up duration was more than 2 years.ResultsAmong the 73 patients (male 34 cases, female 39 cases; age 20–69 years, average 51.4), vertigo was controlled effectively for 66 cases (90.4%) after 2 years of follow-up; 45 cases (61.6%) were completely controlled, and 21 cases (28.8%) were substantially controlled in this study. The patients of 16.4% had hearing loss with more than 10 dB change based on the four-tone average (0.5, 1, 2 and 3 kHz). No patient had a facial nerve weakness, cerebrospinal fluid leakage, or other complications.ConclusionResection of the lateral wall of the endolymphatic sac, which can effectively control vertiginous symptoms in intractable MD patients, represents an effective and safe therapy for this disease. Resection of the lateral wall of the endolymphatic sac is expected to be used as an alternative treatment for MD.https://www.frontiersin.org/articles/10.3389/fneur.2022.827462/fullMeniere's diseasevertigosensorineural hearing lossresection of the lateral wall of the endolymphatic sacsurgery |
| spellingShingle | Daogong Zhang Yafeng Lv Xiaofei Li Yongdong Song Ligang Kong Zhaomin Fan Haibo Wang Efficacy of Resection of Lateral Wall of Endolymphatic Sac for Treatment of Meniere's Disease Frontiers in Neurology Meniere's disease vertigo sensorineural hearing loss resection of the lateral wall of the endolymphatic sac surgery |
| title | Efficacy of Resection of Lateral Wall of Endolymphatic Sac for Treatment of Meniere's Disease |
| title_full | Efficacy of Resection of Lateral Wall of Endolymphatic Sac for Treatment of Meniere's Disease |
| title_fullStr | Efficacy of Resection of Lateral Wall of Endolymphatic Sac for Treatment of Meniere's Disease |
| title_full_unstemmed | Efficacy of Resection of Lateral Wall of Endolymphatic Sac for Treatment of Meniere's Disease |
| title_short | Efficacy of Resection of Lateral Wall of Endolymphatic Sac for Treatment of Meniere's Disease |
| title_sort | efficacy of resection of lateral wall of endolymphatic sac for treatment of meniere s disease |
| topic | Meniere's disease vertigo sensorineural hearing loss resection of the lateral wall of the endolymphatic sac surgery |
| url | https://www.frontiersin.org/articles/10.3389/fneur.2022.827462/full |
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