Urinary TERT promoter mutations as non-invasive biomarkers for the comprehensive detection of urothelial cancerResearch in context

Urinary TERT promoter mutations as non-invasive biomarkers for the comprehensive detection of urothelial cancerResearch in context

Background: Recurrent mutations in the promoter of the telomerase reverse transcriptase (TERT) gene (C228T and C250T) detected in tumours and cells shed into urine of urothelial cancer (UC) patients are putative biomarkers for UC detection and monitoring. However, the possibility of detecting these...

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Main Authors: Patrice Hodonou Avogbe, Arnaud Manel, Emmanuel Vian, Geoffroy Durand, Nathalie Forey, Catherine Voegele, Maria Zvereva, Md Ismail Hosen, Sonia Meziani, Berengere De Tilly, Gilles Polo, Olesia Lole, Pauline Francois, Tiffany Myriam Delhomme, Christine Carreira, Sara Monteiro-Reis, Rui Henrique, Behnoush Abedi-Ardekani, Graham Byrnes, Matthieu Foll, Elisabete Weiderpass, James McKay, Carmen Jeronimo, Ghislaine Scelo, Florence Le Calvez-Kelm
Format: Article
Language:English
Published: Elsevier 2019-06-01
Series:EBioMedicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396419303056

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