Synthesis of Novel Steroid-Peptoid Hybrid Macrocycles by Multiple Multicomponent Macrocyclizations Including Bifunctional Building Blocks (MiBs)

Synthesis of Novel Steroid-Peptoid Hybrid Macrocycles by Multiple Multicomponent Macrocyclizations Including Bifunctional Building Blocks (MiBs)

Two new groups of cholane-peptoid hybrid macrocycles were produced by implementing novel combinations of the MiB methodology. Steroid-based hybrid macrolactams including heterocycle and aryl moieties were obtained by utilizing cholanic dicarboxylic acids and diamines in a bidirectional double Ugi-Fo...

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Bibliografiske detaljer
Main Authors: Ludger A. Wessjohann, Daniel G. Rivera
Format: Article
Sprog:English
Udgivet: MDPI AG 2007-08-01
Serier:Molecules
Fag:
Bile acids
macrocycles
steroids
peptoids
Ugi reaction
multicomponent reaction
Online adgang:http://www.mdpi.com/1420-3049/12/8/1890/

Internet

http://www.mdpi.com/1420-3049/12/8/1890/

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