Molecular imaging in the management of cervical cancer

Positron emission tomography (PET), magnetic resonance imaging (MRI), and integrated 18-fluorodeoxyglucose (18F-FDG) PET/computed tomography are valuable techniques for assessing prognosis, treatment response after the completion of concurrent chemoradiation, suspicious or documented recurrence, une...

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Main Authors: Chyong-Huey Lai, Tzu-Chen Yen, Koon-Kwan Ng
Format: Article
Language:English
Published: Elsevier 2012-08-01
Series:Journal of the Formosan Medical Association
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0929664612001908
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author Chyong-Huey Lai
Tzu-Chen Yen
Koon-Kwan Ng
author_facet Chyong-Huey Lai
Tzu-Chen Yen
Koon-Kwan Ng
author_sort Chyong-Huey Lai
collection DOAJ
description Positron emission tomography (PET), magnetic resonance imaging (MRI), and integrated 18-fluorodeoxyglucose (18F-FDG) PET/computed tomography are valuable techniques for assessing prognosis, treatment response after the completion of concurrent chemoradiation, suspicious or documented recurrence, unexplained post therapy elevations in tumor markers, and the response to salvage treatment when managing cervical cancer. However, PET plays a limited role in the primary staging of MRI-defined node-negative patients. Currently, 18F-FDG is still the only tracer approved for routine use, but several novel targeting PET compounds, high-Tesla MRI machines, diffusion-weighted imaging without contrast, and dynamic nuclear polarized-enhanced 13C-MR spectroscopic imaging may hold promising applications.
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spelling doaj.art-41bd72e95bb04d2f90605f2bf9f50d9b2022-12-22T03:51:53ZengElsevierJournal of the Formosan Medical Association0929-66462012-08-01111841242010.1016/j.jfma.2012.02.024Molecular imaging in the management of cervical cancerChyong-Huey Lai0Tzu-Chen Yen1Koon-Kwan Ng2Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taoyuan, TaiwanDepartment of Nuclear Medicine, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taoyuan, TaiwanDepartment of Medical Imaging and Intervention, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taoyuan, TaiwanPositron emission tomography (PET), magnetic resonance imaging (MRI), and integrated 18-fluorodeoxyglucose (18F-FDG) PET/computed tomography are valuable techniques for assessing prognosis, treatment response after the completion of concurrent chemoradiation, suspicious or documented recurrence, unexplained post therapy elevations in tumor markers, and the response to salvage treatment when managing cervical cancer. However, PET plays a limited role in the primary staging of MRI-defined node-negative patients. Currently, 18F-FDG is still the only tracer approved for routine use, but several novel targeting PET compounds, high-Tesla MRI machines, diffusion-weighted imaging without contrast, and dynamic nuclear polarized-enhanced 13C-MR spectroscopic imaging may hold promising applications.http://www.sciencedirect.com/science/article/pii/S0929664612001908cervical cancermolecular imagingMRIPETPET/CT
spellingShingle Chyong-Huey Lai
Tzu-Chen Yen
Koon-Kwan Ng
Molecular imaging in the management of cervical cancer
Journal of the Formosan Medical Association
cervical cancer
molecular imaging
MRI
PET
PET/CT
title Molecular imaging in the management of cervical cancer
title_full Molecular imaging in the management of cervical cancer
title_fullStr Molecular imaging in the management of cervical cancer
title_full_unstemmed Molecular imaging in the management of cervical cancer
title_short Molecular imaging in the management of cervical cancer
title_sort molecular imaging in the management of cervical cancer
topic cervical cancer
molecular imaging
MRI
PET
PET/CT
url http://www.sciencedirect.com/science/article/pii/S0929664612001908
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AT tzuchenyen molecularimaginginthemanagementofcervicalcancer
AT koonkwanng molecularimaginginthemanagementofcervicalcancer