Tooth loss-related dietary patterns and cognitive impairment in an elderly Japanese population: The Nakajima study.
Although several studies have demonstrated a potential correlation of dietary patterns with cognitive function, the relationship between tooth loss and dietary patterns and cognitive function have not been identified. In this cross-sectional study, we used a reduced rank regression (RRR) analysis, a...
| Main Authors: | , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2018-01-01
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| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC5854423?pdf=render |
| _version_ | 1819011103144804352 |
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| author | Mai Ishimiya Hiroyuki Nakamura Yutaka Kobayashi Moeko Noguchi-Shinohara Chiemi Abe Chiaki Dohmoto Yoshihisa Ikeda Kahori Tokuno Kazuhiro Ooi Masami Yokokawa Kazuo Iwasa Kiyonobu Komai Shuichi Kawashiri Masahito Yamada |
| author_facet | Mai Ishimiya Hiroyuki Nakamura Yutaka Kobayashi Moeko Noguchi-Shinohara Chiemi Abe Chiaki Dohmoto Yoshihisa Ikeda Kahori Tokuno Kazuhiro Ooi Masami Yokokawa Kazuo Iwasa Kiyonobu Komai Shuichi Kawashiri Masahito Yamada |
| author_sort | Mai Ishimiya |
| collection | DOAJ |
| description | Although several studies have demonstrated a potential correlation of dietary patterns with cognitive function, the relationship between tooth loss and dietary patterns and cognitive function have not been identified. In this cross-sectional study, we used a reduced rank regression (RRR) analysis, a technique used previously to observe dietary patterns based on the intakes of nutrients or levels of biomarkers associated with the condition of interest, to identify tooth loss-related dietary patterns and investigate the associations of such patterns with cognitive impairment in 334 community-dwelling Japanese subjects aged ≥ 60 years. According to Pearson correlation coefficients, the intakes of six nutrients (ash content, sodium, zinc, vitamin B1, α- and β-carotene) correlated significantly with the number of remaining teeth. Using RRR analysis, we extracted four dietary patterns in our subject population that explained 86.67% of the total variation in the intakes of these six nutrients. Particularly, dietary pattern 1 (DP1) accounted for 52.2% of the total variation. Food groups with factor loadings of ≥ 0.2 included pickled green leafy vegetables, lettuce/cabbage, green leaves vegetables, cabbage, carrots/squash; by contrast, rice had a factor loading of <-0.2. In a multivariate regression analysis, the adjusted odds ratios regarding the prevalence of cognitive impairment for the lowest, middle and highest tertiles of the DP1 score were 1.00 (reference), 1.224 (95% confidence interval [CI]: 0.611-2.453) and 0.427 (95% CI: 0.191-0.954), respectively. To our knowledge, this is the first report to show that tooth loss-related dietary patterns are associated with a high prevalence of cognitive impairment. These results may motivate changes in dental treatment and the dietary behaviours and thereby lower the risk of cognitive impairment. |
| first_indexed | 2024-12-21T01:22:50Z |
| format | Article |
| id | doaj.art-41c06b2f614549ef914a5a3f4d1caffe |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-12-21T01:22:50Z |
| publishDate | 2018-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-41c06b2f614549ef914a5a3f4d1caffe2022-12-21T19:20:36ZengPublic Library of Science (PLoS)PLoS ONE1932-62032018-01-01133e019450410.1371/journal.pone.0194504Tooth loss-related dietary patterns and cognitive impairment in an elderly Japanese population: The Nakajima study.Mai IshimiyaHiroyuki NakamuraYutaka KobayashiMoeko Noguchi-ShinoharaChiemi AbeChiaki DohmotoYoshihisa IkedaKahori TokunoKazuhiro OoiMasami YokokawaKazuo IwasaKiyonobu KomaiShuichi KawashiriMasahito YamadaAlthough several studies have demonstrated a potential correlation of dietary patterns with cognitive function, the relationship between tooth loss and dietary patterns and cognitive function have not been identified. In this cross-sectional study, we used a reduced rank regression (RRR) analysis, a technique used previously to observe dietary patterns based on the intakes of nutrients or levels of biomarkers associated with the condition of interest, to identify tooth loss-related dietary patterns and investigate the associations of such patterns with cognitive impairment in 334 community-dwelling Japanese subjects aged ≥ 60 years. According to Pearson correlation coefficients, the intakes of six nutrients (ash content, sodium, zinc, vitamin B1, α- and β-carotene) correlated significantly with the number of remaining teeth. Using RRR analysis, we extracted four dietary patterns in our subject population that explained 86.67% of the total variation in the intakes of these six nutrients. Particularly, dietary pattern 1 (DP1) accounted for 52.2% of the total variation. Food groups with factor loadings of ≥ 0.2 included pickled green leafy vegetables, lettuce/cabbage, green leaves vegetables, cabbage, carrots/squash; by contrast, rice had a factor loading of <-0.2. In a multivariate regression analysis, the adjusted odds ratios regarding the prevalence of cognitive impairment for the lowest, middle and highest tertiles of the DP1 score were 1.00 (reference), 1.224 (95% confidence interval [CI]: 0.611-2.453) and 0.427 (95% CI: 0.191-0.954), respectively. To our knowledge, this is the first report to show that tooth loss-related dietary patterns are associated with a high prevalence of cognitive impairment. These results may motivate changes in dental treatment and the dietary behaviours and thereby lower the risk of cognitive impairment.http://europepmc.org/articles/PMC5854423?pdf=render |
| spellingShingle | Mai Ishimiya Hiroyuki Nakamura Yutaka Kobayashi Moeko Noguchi-Shinohara Chiemi Abe Chiaki Dohmoto Yoshihisa Ikeda Kahori Tokuno Kazuhiro Ooi Masami Yokokawa Kazuo Iwasa Kiyonobu Komai Shuichi Kawashiri Masahito Yamada Tooth loss-related dietary patterns and cognitive impairment in an elderly Japanese population: The Nakajima study. PLoS ONE |
| title | Tooth loss-related dietary patterns and cognitive impairment in an elderly Japanese population: The Nakajima study. |
| title_full | Tooth loss-related dietary patterns and cognitive impairment in an elderly Japanese population: The Nakajima study. |
| title_fullStr | Tooth loss-related dietary patterns and cognitive impairment in an elderly Japanese population: The Nakajima study. |
| title_full_unstemmed | Tooth loss-related dietary patterns and cognitive impairment in an elderly Japanese population: The Nakajima study. |
| title_short | Tooth loss-related dietary patterns and cognitive impairment in an elderly Japanese population: The Nakajima study. |
| title_sort | tooth loss related dietary patterns and cognitive impairment in an elderly japanese population the nakajima study |
| url | http://europepmc.org/articles/PMC5854423?pdf=render |
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