Relevance of skin-prick test and immunoglobulin E estimation in pigeon-exposure asthma patients
Background Pigeon exposure is common in India due to its cultural and religious practice. Hypersensitivity to pigeon allergen is well known as pigeon breeder disease. Limited data also show that pigeon allergen was associated with increased asthma. The aim of this study is to evaluate skin-prick tes...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2021-01-01
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| Series: | Egyptian Journal of Chest Disease and Tuberculosis |
| Subjects: | |
| Online Access: | http://www.ejcdt.eg.net/article.asp?issn=0422-7638;year=2021;volume=70;issue=4;spage=433;epage=440;aulast=Mavi |
| _version_ | 1811239085474316288 |
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| author | Anil K Mavi Sonam Spalgais Kamal Singh Manoj Kumar Raj Kumar |
| author_facet | Anil K Mavi Sonam Spalgais Kamal Singh Manoj Kumar Raj Kumar |
| author_sort | Anil K Mavi |
| collection | DOAJ |
| description | Background Pigeon exposure is common in India due to its cultural and religious practice. Hypersensitivity to pigeon allergen is well known as pigeon breeder disease. Limited data also show that pigeon allergen was associated with increased asthma. The aim of this study is to evaluate skin-prick test (SPT) and immunoglobulin E (IgE) levels in pigeon-exposed asthmatics.
Patients and methods It is a prospective observational study with 200 asthma patients as per Global Initiative for Asthma guidelines. As per the history of exposure to pigeons, patients were divided into two groups: exposed and nonexposed asthmatics. All patients underwent SPT against CAA with pigeon allergen and measurements of serum IgE. The result was compared between two groups.
Results Out of 200 patients with mean age of 29.83±9.92 years, 108 had pigeon exposure. The SPT against CAA sensitivity was positive in 74% exposed and 63% nonexposed groups. While SPT against pigeon allergen was positive in 17 (15.7%) in exposed patients. The mean total IgE was higher in exposed asthmatics but not significant (538.75±248.5 and 510.2±220.1 IU/ml, P=0.0078). The mean specific IgE against pigeon dropping and feather was significantly higher in exposed asthmatics (0.4513±1.01 and 0.1957±0.179 KUA/l, P=0.003; 0.3644±0.329 and 0.1176±0.116 KUA/l, P=0.000).
Conclusion The asthmatic patients with exposure to pigeons had higher SPT against pigeon allergen and higher total and specific IgE against pigeon antigens. This may be one of the reasons for higher asthma in urban cities. |
| first_indexed | 2024-04-12T12:54:39Z |
| format | Article |
| id | doaj.art-41c74ba2fb034f41aec7767192c45d6c |
| institution | Directory Open Access Journal |
| issn | 0422-7638 2090-9950 |
| language | English |
| last_indexed | 2024-04-12T12:54:39Z |
| publishDate | 2021-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Egyptian Journal of Chest Disease and Tuberculosis |
| spelling | doaj.art-41c74ba2fb034f41aec7767192c45d6c2022-12-22T03:32:22ZengWolters Kluwer Medknow PublicationsEgyptian Journal of Chest Disease and Tuberculosis0422-76382090-99502021-01-0170443344010.4103/ecdt.ecdt_18_21Relevance of skin-prick test and immunoglobulin E estimation in pigeon-exposure asthma patientsAnil K MaviSonam SpalgaisKamal SinghManoj KumarRaj KumarBackground Pigeon exposure is common in India due to its cultural and religious practice. Hypersensitivity to pigeon allergen is well known as pigeon breeder disease. Limited data also show that pigeon allergen was associated with increased asthma. The aim of this study is to evaluate skin-prick test (SPT) and immunoglobulin E (IgE) levels in pigeon-exposed asthmatics. Patients and methods It is a prospective observational study with 200 asthma patients as per Global Initiative for Asthma guidelines. As per the history of exposure to pigeons, patients were divided into two groups: exposed and nonexposed asthmatics. All patients underwent SPT against CAA with pigeon allergen and measurements of serum IgE. The result was compared between two groups. Results Out of 200 patients with mean age of 29.83±9.92 years, 108 had pigeon exposure. The SPT against CAA sensitivity was positive in 74% exposed and 63% nonexposed groups. While SPT against pigeon allergen was positive in 17 (15.7%) in exposed patients. The mean total IgE was higher in exposed asthmatics but not significant (538.75±248.5 and 510.2±220.1 IU/ml, P=0.0078). The mean specific IgE against pigeon dropping and feather was significantly higher in exposed asthmatics (0.4513±1.01 and 0.1957±0.179 KUA/l, P=0.003; 0.3644±0.329 and 0.1176±0.116 KUA/l, P=0.000). Conclusion The asthmatic patients with exposure to pigeons had higher SPT against pigeon allergen and higher total and specific IgE against pigeon antigens. This may be one of the reasons for higher asthma in urban cities.http://www.ejcdt.eg.net/article.asp?issn=0422-7638;year=2021;volume=70;issue=4;spage=433;epage=440;aulast=Maviasthmaimmunoglobulin epigeonskin-prick test |
| spellingShingle | Anil K Mavi Sonam Spalgais Kamal Singh Manoj Kumar Raj Kumar Relevance of skin-prick test and immunoglobulin E estimation in pigeon-exposure asthma patients Egyptian Journal of Chest Disease and Tuberculosis asthma immunoglobulin e pigeon skin-prick test |
| title | Relevance of skin-prick test and immunoglobulin E estimation in pigeon-exposure asthma patients |
| title_full | Relevance of skin-prick test and immunoglobulin E estimation in pigeon-exposure asthma patients |
| title_fullStr | Relevance of skin-prick test and immunoglobulin E estimation in pigeon-exposure asthma patients |
| title_full_unstemmed | Relevance of skin-prick test and immunoglobulin E estimation in pigeon-exposure asthma patients |
| title_short | Relevance of skin-prick test and immunoglobulin E estimation in pigeon-exposure asthma patients |
| title_sort | relevance of skin prick test and immunoglobulin e estimation in pigeon exposure asthma patients |
| topic | asthma immunoglobulin e pigeon skin-prick test |
| url | http://www.ejcdt.eg.net/article.asp?issn=0422-7638;year=2021;volume=70;issue=4;spage=433;epage=440;aulast=Mavi |
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