Myeloid PFKFB3-mediated glycolysis promotes kidney fibrosis

Myeloid PFKFB3-mediated glycolysis promotes kidney fibrosis

Excessive renal fibrosis is a common pathology in progressive chronic kidney diseases. Inflammatory injury and aberrant repair processes contribute to the development of kidney fibrosis. Myeloid cells, particularly monocytes/macrophages, play a crucial role in kidney fibrosis by releasing their proi...

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Bibliographic Details
Main Authors:	Qiuhua Yang, Emily Huo, Yongfeng Cai, Zhidan Zhang, Charles Dong, John M. Asara, Huidong Shi, Qingqing Wei
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-11-01
Series:	Frontiers in Immunology
Subjects:	macrophage glycolysis renal fibrosis PFKFB3 inflammation
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2023.1259434/full

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