Genetic polymorphism of caprine stearoyl-coA desaturase (SCD) gene and their relationship with blood cholesterol, triglyceride and pre-weaning growth traits of mixed breeds of goats in southern Thailand
The present study attempts to identify genetic polymorphisms of stearoyl-coA desaturase (SCD) gene and their relationship with blood cholesterol, triglyceride and pre-weaning growth traits in a goat population in southern Thailand. Genetic variability in caprine SCD was analyzed in 290 animals belo...
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| Format: | Article |
| Language: | English |
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Indian Council of Agricultural Research
2016-04-01
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| Series: | Indian Journal of Animal Sciences |
| Subjects: | |
| Online Access: | https://epubs.icar.org.in/index.php/IJAnS/article/view/57776 |
| _version_ | 1797740438001549312 |
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| author | CHINA SUPAKORN WINAI PRALOMKARN SORNTHEP TUMWASORN |
| author_facet | CHINA SUPAKORN WINAI PRALOMKARN SORNTHEP TUMWASORN |
| author_sort | CHINA SUPAKORN |
| collection | DOAJ |
| description |
The present study attempts to identify genetic polymorphisms of stearoyl-coA desaturase (SCD) gene and their relationship with blood cholesterol, triglyceride and pre-weaning growth traits in a goat population in southern Thailand. Genetic variability in caprine SCD was analyzed in 290 animals belonging to several types of Thai native (TN), Anglo-nubian (AN), Boer (B) and Saanen (SA) breed crosses by PCR-SSCP and DNA sequencing. Four SNPs were identified in exon3 (A/G), exon5 (C/T), exon6 (C/G) and 3’untranslated region (3’UTR) (TGT deletion). Five haplotypes (A, B, C, D and E) were constructed. Haplotype frequency B was the highest (0.50) but haplotype frequency C was the lowest (0.01). Haplotype effect of SCD gene had influenced on blood cholesterol, triglyceride, weaning weight and growth rate. Individuals with haplotype C had significant lowest triglyceride, weaning weight and growth rate (P<0.05). Also, this haplotype could be culled for growth improvement in this population.
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| first_indexed | 2024-03-12T14:12:27Z |
| format | Article |
| id | doaj.art-41c89f94aef646dd8b04fc80bd9c5571 |
| institution | Directory Open Access Journal |
| issn | 0367-8318 2394-3327 |
| language | English |
| last_indexed | 2024-03-12T14:12:27Z |
| publishDate | 2016-04-01 |
| publisher | Indian Council of Agricultural Research |
| record_format | Article |
| series | Indian Journal of Animal Sciences |
| spelling | doaj.art-41c89f94aef646dd8b04fc80bd9c55712023-08-21T06:31:43ZengIndian Council of Agricultural ResearchIndian Journal of Animal Sciences0367-83182394-33272016-04-0186410.56093/ijans.v86i4.57776Genetic polymorphism of caprine stearoyl-coA desaturase (SCD) gene and their relationship with blood cholesterol, triglyceride and pre-weaning growth traits of mixed breeds of goats in southern ThailandCHINA SUPAKORN0WINAI PRALOMKARN1SORNTHEP TUMWASORN2School of Agricultural Technology,Walailak University, Nakhon Si Thammarat 80161 ThailandSchool of Agricultural Technology,Walailak University, Nakhon Si Thammarat 80161 ThailandSchool of Agricultural Technology,Walailak University, Nakhon Si Thammarat 80161 Thailand The present study attempts to identify genetic polymorphisms of stearoyl-coA desaturase (SCD) gene and their relationship with blood cholesterol, triglyceride and pre-weaning growth traits in a goat population in southern Thailand. Genetic variability in caprine SCD was analyzed in 290 animals belonging to several types of Thai native (TN), Anglo-nubian (AN), Boer (B) and Saanen (SA) breed crosses by PCR-SSCP and DNA sequencing. Four SNPs were identified in exon3 (A/G), exon5 (C/T), exon6 (C/G) and 3’untranslated region (3’UTR) (TGT deletion). Five haplotypes (A, B, C, D and E) were constructed. Haplotype frequency B was the highest (0.50) but haplotype frequency C was the lowest (0.01). Haplotype effect of SCD gene had influenced on blood cholesterol, triglyceride, weaning weight and growth rate. Individuals with haplotype C had significant lowest triglyceride, weaning weight and growth rate (P<0.05). Also, this haplotype could be culled for growth improvement in this population. https://epubs.icar.org.in/index.php/IJAnS/article/view/57776Blood cholesterolGoatPre-weaning growth traitsStearoyl-coA desaturase (SCD) geneTriglyceride |
| spellingShingle | CHINA SUPAKORN WINAI PRALOMKARN SORNTHEP TUMWASORN Genetic polymorphism of caprine stearoyl-coA desaturase (SCD) gene and their relationship with blood cholesterol, triglyceride and pre-weaning growth traits of mixed breeds of goats in southern Thailand Indian Journal of Animal Sciences Blood cholesterol Goat Pre-weaning growth traits Stearoyl-coA desaturase (SCD) gene Triglyceride |
| title | Genetic polymorphism of caprine stearoyl-coA desaturase (SCD) gene and their relationship with blood cholesterol, triglyceride and pre-weaning growth traits of mixed breeds of goats in southern Thailand |
| title_full | Genetic polymorphism of caprine stearoyl-coA desaturase (SCD) gene and their relationship with blood cholesterol, triglyceride and pre-weaning growth traits of mixed breeds of goats in southern Thailand |
| title_fullStr | Genetic polymorphism of caprine stearoyl-coA desaturase (SCD) gene and their relationship with blood cholesterol, triglyceride and pre-weaning growth traits of mixed breeds of goats in southern Thailand |
| title_full_unstemmed | Genetic polymorphism of caprine stearoyl-coA desaturase (SCD) gene and their relationship with blood cholesterol, triglyceride and pre-weaning growth traits of mixed breeds of goats in southern Thailand |
| title_short | Genetic polymorphism of caprine stearoyl-coA desaturase (SCD) gene and their relationship with blood cholesterol, triglyceride and pre-weaning growth traits of mixed breeds of goats in southern Thailand |
| title_sort | genetic polymorphism of caprine stearoyl coa desaturase scd gene and their relationship with blood cholesterol triglyceride and pre weaning growth traits of mixed breeds of goats in southern thailand |
| topic | Blood cholesterol Goat Pre-weaning growth traits Stearoyl-coA desaturase (SCD) gene Triglyceride |
| url | https://epubs.icar.org.in/index.php/IJAnS/article/view/57776 |
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